ChemicalBook > Product Catalog >Pharmaceutical intermediates >Bulk Drug Intermediates >Dehydronandrolone Acetate
Dehydronandrolone Acetate
- CAS No.
- 2590-41-2
- Chemical Name:
- Dehydronandrolone Acetate
- Synonyms
- Dehydronandrolone Acetate;Dehydronandrolon acetate;6-DEHYDRONANDROLONE ACETATE;17b-Acetyloxy-estra-4,6-diene-3-one;4,6-ESTRADIEN-17-BETA-OL-3-ONE ACETATE;Dehydrondrolon;DEHYDRONANDROLON;6-Dehydroandrolone acetate;Dehydronandrolone-6 Acetate;Dehydronandrolon(2590-41-2)
- CBNumber:
- CB9390951
- Molecular Formula:
- C20H26O3
- Molecular Weight:
- 314.42
- MOL File:
- 2590-41-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/5/18 8:51:57
| Melting point | 95-98?C |
|---|---|
| Boiling point | 457.4±45.0 °C(Predicted) |
| Density | 1.15±0.1 g/cm3(Predicted) |
| storage temp. | Controlled Substance, -20°C Freezer |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| color | Off-White to Pale Yellow |
| InChI | InChI=1/C20H26O3/c1-12(21)23-19-8-7-18-17-5-3-13-11-14(22)4-6-15(13)16(17)9-10-20(18,19)2/h3,5,11,15-19H,4,6-10H2,1-2H3/t15-,16+,17+,18-,19-,20-/s3 |
| InChIKey | OGUASZAAVFYYIL-SBVYDUMINA-N |
| SMILES | [C@@]12([H])CC[C@H](OC(=O)C)[C@@]1(C)CC[C@]1([H])[C@@]3([H])CCC(=O)C=C3C=C[C@@]21[H] |&1:0,4,9,13,15,25,r| |
| CAS DataBase Reference | 2590-41-2(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H361 |
| Precautionary statements | P501-P202-P201-P280-P308+P313-P405 |
Dehydronandrolone Acetate price More Price(2)
Dehydronandrolone Acetate Chemical Properties,Uses,Production
Description
Dehydronandrolone acetate is a critical precursor in the synthesis of C7-functionalized steroidal drugs such as the new anti-breast cancer drug Fulvestrant, the treatment of menopause and postmenopausal syndrome drug Tibolone, as well as the highly effective protein anabolic hormone Mibolone. Nandrolone as starting material was first subjected to simultaneous acylation with acetic anhydride and acetyl chloride to form the intermediate, which was then brominated with N-bromosuccinimide (NBS) under basic conditions to eliminate one molecule of HBr to produce Dehydronandrolone acetate (73% yield)[1].
Chemical Properties
Pale Yellow Solid
Uses
Tibolone intermediate.
References
[1] Zili Zhang and Aitao Li*. “A Designed Chemoenzymatic Route for Efficient Synthesis of 6-Dehydronandrolone Acetate: A Key Precursor in the Synthesis of C7-Functionalized Steroidal Drugs.” ACS Catalysis 13 19 (2023): 13111–13116.
Dehydronandrolone Acetate Preparation Products And Raw materials
Global( 200)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6768 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6514 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6100 | 58 | Inquiry |
| Liaoning Pharmaceutical Innovation Co., Ltd | +8616588669988 | China | 151 | 58 | Inquiry |
| Hangzhou ICH Biofarm Co., Ltd | +86-0571-28186870; +undefined8613073685410 | China | 1015 | 58 | Inquiry |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | China | 615 | 58 | Inquiry |
| Shandong Hanjiang Chemical Co., Ltd | +86-0533-2066820 +8618369939125 | China | 339 | 58 | Inquiry |
| Hebei Kangcang new material Technology Co., LTD | +8615713292910 | China | 341 | 58 | Inquiry |
| hebei hongtan Biotechnology Co., Ltd | +852-6619 3215 +86-17731935328 | China | 970 | 58 | Inquiry |
2590-41-2(Dehydronandrolone Acetate)Related Search:
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17-ACETOXYESTRA-4,6-DIEN-3-ONE
DEHYDRONANDROLON
(8R,9S,13S,14S,17S)-13-Methyl-3-oxo-2,3,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate
Dehydronandrolone-6 Acetate
Acetic acid 13-Methyl-3-oxo-2,3,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl este
(8R,9S,10R,13S,14S,17S)-13-Methyl-3-oxo-2,3,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate
Estra-4,6-dien-3-one,17-(acetyloxy)-, (17b)-
Dehydronandrolon 17b-Acetyloxy-estra-4,6-diene-3-one
Dehydrondrolon
Dehydrogenation nandrolone acetate
acetic acid (13-methyl-3-oxo-2,8,9,10,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-yl) ester
Dehydronandrolon(2590-41-2)
Estra-4,6-dien-3-one, 17-(acetyloxy)-, (17β)-
17beta-Acetoxyestra-4,6-dien-3-one
DEHYDRONANDROLONE ACETATE CAS 2590-41-2
Dehydronandrolon acetate
Dehydronandrolone Acetate
6-DEHYDRONANDROLONE ACETATE
4,6-ESTRADIEN-17-BETA-OL-3-ONE ACETATE
17b-Acetyloxy-estra-4,6-diene-3-one
6-Dehydroandrolone acetate
(8R,9S,13S,Chemicalbook14S,17S)-13-Methyl-3-oxo-2,3,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-ylacetate
6-dehydro-19-nortestosterone acetate
2590-41-2
1642-62-0
C20H26O3
API
Intermediates
Intermediates & Fine Chemicals
Pharmaceuticals
Steroids