Nandrolone Decanoate
- CAS No.
- 360-70-3
- Chemical Name:
- Nandrolone Decanoate
- Synonyms
- DECADURABOLIN;Anabolicum;Nandrolone Deconate;Nandrolone Decanoate (DECA);19-NORTESTOSTERONE 17-DECANOATE;retabolil;Decanofort;Extraboline;Deca-Hybolin;deca-durabol
- CBNumber:
- CB0396051
- Molecular Formula:
- C28H44O3
- Molecular Weight:
- 428.65
- MOL File:
- 360-70-3.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/11/11 20:33:26
| Melting point | 33-37°C |
|---|---|
| alpha | 32 º |
| Boiling point | 483.46°C (rough estimate) |
| Density | 1.0406 (rough estimate) |
| refractive index | 1.4700 (estimate) |
| storage temp. | 2-8°C |
| solubility | 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.8 mg/mL |
| form | powder |
| color | white to light yellow |
| Water Solubility | 664ug/L(37 ºC) |
| InChIKey | JKWKMORAXJQQSR-MOPIKTETSA-N |
| SMILES | [C@@]12([H])CC[C@H](OC(=O)CCCCCCCCC)[C@@]1(C)CC[C@]1([H])[C@@]3([H])CCC(=O)C=C3CC[C@@]21[H] |&1:0,4,17,21,23,33,r| |
| CAS DataBase Reference | 360-70-3 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H351-H360FD | |||||||||
| Precautionary statements | P201-P202-P280-P308+P313-P405-P501 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 40 | |||||||||
| Safety Statements | 22-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | KG7967000 | |||||||||
| HS Code | 2937290000 | |||||||||
| Toxicity | LD50 intraperitoneal in mouse: > 566mg/kg | |||||||||
| NFPA 704 |
|
Nandrolone Decanoate Chemical Properties,Uses,Production
Description
Nandrolone decanoate, also known as nandrolone caprinate, is an alkylated anabolic steroid indicated in the management of anemia of renal insufficiency and as an adjunct therapy in the treatment of senile and postmenopausal osteoporosis. The process for creating esters of [nandrolone] was patented in Spain in 1959 and in 1960, it was described as having a long duration of action and strong anabolic effect compared to nandrolone and other esters. Nandrolone decanoate was granted FDA approval on 5 October 1962.
Chemical Properties
White or almost white, crystalline powder.
Uses
Nandrolone Decanoate is an anabolic steroid. Nandrolone decanoate is used in the treatment of osteoporosis in postmenopausal women. Nandrolone Decanoate is also used for some aplastic anemias. Control led Substance.
World Health Organization (WHO)
Nandrolone decanoate, an anabolic steroid, was introduced in 1962. In 1982, low dosage preparations were prohibited in Bangladesh due to inadmissible promotion of products containing anabolic steroids for malnourished children. Higher dosage preparations of nandrolone decanoate remain available in many countries, including Bangladesh, for several highly specific but limited indications that apply to patients with chronic debilitating and emaciating diseases, particularly associated with neoplasia and some types of aplastic anaemia.
General Description
Nandrolone decanoate,17β-hydroxyestr-4-en-3-one 17-decanoate, has been used inthe management of certain anemias, but the availability oferythropoietin has greatly reduced this use.
Biochem/physiol Actions
Compared to testosterone propionate, nandrolone decanoate is considered to have strong anabolic effects but weak androgenic effects (potency ratios of 3.29–4.92 and 0.31–0.41). In particular, nandrolone esters are thought to have the highest ratio of anabolic to androgenic effects of any AAS. The low androgenicity of nandrolone decanoate is thought to be due to the fact that nandrolone is inactivated by 5α-reductase via transformation into the low-affinity androgen receptor (AR) ligand 5α-dihydronandrolone. This is thought to result in a lower incidence and magnitude of side effects.Nandrolone decanoate (ND) injection has been classified as a Schedule III controlled substance under the Anabolic Steroids Control Act of 1990. Due to serious health risks, the nonmedical use of AASs is banned by most sports organizations[1].
Side effects
There are many effects of this drug on the human body, and the studies of its side effects can be divided into the following: categories endocrine, cardiovascular, skin, psychiatric, musculoskeletal, excretory, and gastrointestinal disorders.
The most common side effects were: endocrine disorders (virilization, gynecomastia, hormonal disorders, cholesterol and lipid disorders, genital and infertility issues); cardiovascular disorders (vascular damage, coagulation disorders, arteriosus hypertension); skin disorders (pricking, acne, skin spots); psychiatric disorders (aggressiveness, mood disorders, sleep disorders, anxiety); musculoskeletal disorders (tendon ruptures); excretory disorders (organ damage); gastrointestinal disorders (organ damage and liver adenomas); neurological disorders (seizures); immune disorders (chronic infection relapse; respiratory disorders (sleep apnea syndrome); genetic disorders (genetic damage)[1].
Safety Profile
Experimental reproductiveeffects. When heated to decomposition it emits acridsmoke and irritating fumes.
Nandrolone Decanoate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Gonane Pharma | +91-9819380043 +91-9819380043 | NaviMumbai, India | 192 | 58 | Inquiry |
| Asg Biochem Pvt. Ltd | +91-9650436669 +91-9650436669 | New Delhi, India | 25 | 58 | Inquiry |
| Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
| PROTECH TELELINKS | +91-8571891912 +91-9855060837 | Himachal Pradesh, India | 62 | 58 | Inquiry |
| Shakti Life Science | +91-9930420063 +91-9930420063 | Maharashtra, India | 28 | 58 | Inquiry |
| Brichem Life Sciences Pvt Ltd | +91-9879109660 +91-9427536568 | Gujarat, India | 11 | 58 | Inquiry |
| Symbiotec Pharma Lab Pvt Ltd | +91-7316676406 +91-7316676405 | Madhya Pradesh, India | 71 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6514 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6739 | 58 | Inquiry |
| Sheth Pharmachem | 08046030722 | Mumbai, India | 8 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Gonane Pharma | 58 |
| Asg Biochem Pvt. Ltd | 58 |
| Ralington Pharma | 58 |
| PROTECH TELELINKS | 58 |
| Shakti Life Science | 58 |
| Brichem Life Sciences Pvt Ltd | 58 |
| Symbiotec Pharma Lab Pvt Ltd | 58 |
| SynZeal Research Pvt Ltd | 58 |
| Pharmaffiliates Analytics and Synthetics P. Ltd | 58 |
| Sheth Pharmachem | 58 |
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