SENKIRKIN
- CAS No.
- 2318-18-5
- Chemical Name:
- SENKIRKIN
- Synonyms
- SENKIKIN;Kushenin;renardin;SENKIRKIN;nsc-89945;RENARIDINE;Senkarkane;senkirkine;renardine[neutral];Renardine (neutral)
- CBNumber:
- CB9427741
- Molecular Formula:
- C19H27NO6
- Molecular Weight:
- 365.42
- MOL File:
- 2318-18-5.mol
- Modify Date:
- 2023/5/25 18:01:23
SENKIRKIN Chemical Properties,Uses,Production
Description
A further hepatotoxiC alkaloid present in Senecio kirkii Hook, S. renardi and Nardosrnia laevigata. The base has [α]25D - 16° (c 1.89, MeOH) or[α]15D - 6.2° (c 1.91, CHCI3). It forms colourless plates when crystallized from either Me2CO or AcOEt and yields a picrate, m.p. 225.5-226°C and a picrolonate, m.p. 109- 110°C. The ultraviolet spectrum shows a single absorption maximum at 219 mp.. Several crystalline salts and derivatives are known, e.g. the aurichloride, m.p. 182.5-183.5°C; platinichloride, m.p. 196-7°C (dec.); bitartrate, m.p. 201°C; reineckate, m.p. 169-171°C; picrate, m.p. 225- 225.5°C; picrolonate, m.p. 138°C and the methiodide, m.p. 194-6°C (dec.). The O-acetate occurs naturally (q.v.) in Senecio kirkii.
Safety Profile
Poison by ingestion and intraperitoneal routes. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of Nox
References
Briggs, Mangan, Russell., J. Chern. Soc., 1891 (1948)
Massagetov, Kuzovkov.,J. Gen. Chern., USSR, 23, 158 (1953)
Danilova, Konovalova., ibid, 30, 1921 (1961)
Danilova, Koretskaya, Utkin., ibid, 31, 3815 (1961)
Wunderlich., Chern. Ind., 2089 (1962)
Briggs et al., J. Chern. Soc., 2492 (1965)
SENKIRKIN Preparation Products And Raw materials
Raw materials
Preparation Products
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| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
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| Chengdu Push Bio-Technology Co., Ltd. | 028-85370565-229 18080489829 | China | 9369 | 60 | Inquiry |