ChemicalBook > Product Catalog >API >Nervous system drugs >Drug Metabolism in Human Brain >PROPENTOFYLLINE

PROPENTOFYLLINE

PROPENTOFYLLINE Structure
CAS No.
55242-55-2
Chemical Name:
PROPENTOFYLLINE
Synonyms
hextol;hoe-285;HWA 285;karsivan;albert-285;PROPENTOFYLLINE;Propentophylline;HOE-285:Hextol:Karsivan;PROPENTOFYLLINE USP/EP/BP;1-(5-oxohexyl)-3-methyl-7-propylxanthine
CBNumber:
CB9432592
Molecular Formula:
C15H22N4O3
Molecular Weight:
306.36
MOL File:
55242-55-2.mol
MSDS File:
SDS
Modify Date:
2023/6/8 9:03:01

PROPENTOFYLLINE Properties

Melting point 64-66°C
Boiling point 541.4±56.0 °C(Predicted)
Density 1.25±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility H2O: soluble12.4mg/mL
pka 0.58±0.70(Predicted)
form solid
color white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332
Precautionary statements  P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312
Hazard Codes  Xn
Risk Statements  20/21/22
WGK Germany  3
RTECS  UO8438700
Toxicity LD50 in male, female mice, male, female rats (mg/kg): 900, 780, 1150, 940 orally; 168, 170, 180, 195 i.v.; 375, 346, 199, 196 i.p.; 450, 508, 400, 338 s.c. (Inazu)
NFPA 704
0
3 0

PROPENTOFYLLINE Chemical Properties,Uses,Production

Description

Propentofylline is a nootropic indicated for cerebrovascular disorders. Other indications currently under investigation include senile dementia, stroke and hypoxia.

Chemical Properties

Off-White Solid

PROPENTOFYLLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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3,7-DIHYDRO-3-METHYL-1-(5-OXOHEXYL)-7-PROPYL-1H-PURINE-2,6-DIONE 3-METHYL-1-[5-OXOHEXYL]-7-PROPYL-XANTHINE PROPENTOFYLLINE 3,7-Dihydro-3-methyl-1-(5-oxohexyl)-7-propyl-1H-purine-2,6-dione, HWA-285, Albert-285, HOE-285, Hextol, Karsivan 1H-Purine-2,6-dione, 3,7-dihydro-3-methyl-1-(5-oxohexyl)-7-propyl- HOE-285:Hextol:Karsivan 3-Methyl-1-(5-oxohexyl)-7-propylxanthine, HWA285, 3,7-Dihydro-3-methyl-1-(5-oxohexyl)-7-propyl-1H-purine-2,6-dione 3-Methyl-1-(5-oxohexyl)-7-propylpurine-2,6-dione 1-(5-oxohexyl)-3-methyl-7-propylxanthine 3,7-dihydro-3-methyl-1-(5-oxohexyl)-7-propyl-1h-purine-6-dione albert-285 hextol hoe-285 karsivan HWA 285 3-Methyl-1-(5-oxohexyl)-7-propyl-1H-purine-2,6(3H,7H)-dione PROPENTOFYLLINE USP/EP/BP Propentophylline 55242-55-2 C15H22N4O3 Cyclic Nucleotide Metabolism G Proteins and Cyclic Nucleotides Phosphodiesterase Inhibitors Cell Signaling and Neuroscience Cell Biology BioChemical All Inhibitors Inhibitors Intermediates & Fine Chemicals Pharmaceuticals