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Tiopronin

Tiopronin Structure
CAS No.
1953-02-2
Chemical Name:
Tiopronin
Synonyms
Thiola;Thiopronin;N-(2-MERCAPTOPROPIONYL)GLYCINE;2-(2-Mercaptopropanamido)acetic acid;Capen;2-MPG;Vincol;SF-572;Thiora;Epatiol
CBNumber:
CB2106227
Molecular Formula:
C5H9NO3S
Molecular Weight:
163.19
MOL File:
1953-02-2.mol
MSDS File:
SDS
Modify Date:
2024/7/12 17:58:41

Tiopronin Properties

Melting point 93-98 °C
Boiling point 418.3±30.0 °C(Predicted)
Density 1.249 (estimate)
refractive index 1.5216 (estimate)
storage temp. Inert atmosphere,2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
form solid
pka 3.36±0.10(Predicted)
color White
Merck 14,9453
BRN 1859822
CAS DataBase Reference 1953-02-2(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P501
Hazard Codes  Xn
Risk Statements  22
Safety Statements  36/37
WGK Germany  3
RTECS  MC0596500
HS Code  2930.90.4950
Toxicity LD50 i.v. in mice: 2.1 g/kg (Fujimura)
NFPA 704
0
1 0

Tiopronin price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) M6635 N-(2-Mercaptopropionyl)glycine 1953-02-2 5G ₹6484.18 2022-06-14 Buy
Sigma-Aldrich(India) M6635 N-(2-Mercaptopropionyl)glycine 1953-02-2 10G ₹9244.55 2022-06-14 Buy
TCI Chemicals (India) T2614 Tiopronin min. 97.0 % 1953-02-2 5G ₹5500 2022-05-26 Buy
TCI Chemicals (India) T2614 Tiopronin min. 97.0 % 1953-02-2 25G ₹14700 2022-05-26 Buy
Product number Packaging Price Buy
M6635 5G ₹6484.18 Buy
M6635 10G ₹9244.55 Buy
T2614 5G ₹5500 Buy
T2614 25G ₹14700 Buy

Tiopronin Chemical Properties,Uses,Production

Description

Tiopronin is a sulfiydryl derivative of N-propylglycine useful in the treatment of cystine urolithiasis in children. It is also reportedly effective in the management of rheumatoid polyarthritis, possibly due to its inhibitory effect on the free oxygen radicals produced by inflammatory macrophages and granulocytes.

Chemical Properties

White Solid

Uses

N-(2-Mercaptopropionyl)glycine or Tiopronin has been used:

  • in the preparation of polyethylenimine (PEI)-coated gold microparticles (PEI-gold) for biolistic delivery of nucleic acids
  • to study the role of reactive oxygen species (ROS) at the reperfusion stage in in vivo isoflurane preconditioning-induced neuroprotection
  • as a ROS inhibitor to study its effect on lysophosphatidylcholine (LPC)-induced inflammasome activation

Tiopronin Preparation Products And Raw materials

Global( 414)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Biophore India Pharmaceuticals Pvt Ltd +91-9100031592 +91-9030907714 Telangana, India 134 58 Inquiry
Laxai Life Sciences +91-4023480125 +91-4023480125 Hyderabad, India 21 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
BIOPHORE INDIA PHARMACEUTICALS PVT LTD +91-4047474545 New Delhi, India 105 58 Inquiry
MSN LIFE SCIENCES PRIVATE LTD +91 84523 34200 New Delhi, India 104 58 Inquiry
Zibo Hangyu Biotechnology Development Co., Ltd +86-0533-2185556 +8617865335152 China 10978 58 Inquiry
A-MERCAPTOPROPIONYL GLYCINE ALPHA-MERCAPTO PROPIONYL GLYCINE LABOTEST-BB LT00451995 TIOPRONIN TOPRONIN (2-Mercaptopropionamido)acetic acid (2-Mercaptopropionyl)glycine Acadione a-Mercaptopropionyglycine BRN 1859822 Capen Captimer CCRIS 1935 DL-(a-Mercaptopropionyl)glycine Epatiol Glycine, N-(2-mercapto-1-oxopropyl)- (9CI) Glycine, N-(2-mercaptopropionyl)- (7CI, 8CI) Hepadigest Meprin (detoxicant) MPG (hepatoprotective) Mucolysin N-(2-Meraptopropionyl)glycine Sutilan Sutilan Cusi Thiolpropionamidoacetic acid Thiopronine Thiosol Tiopronin, Vetranal N-(2-MERCAPTOPROPIONYL)GLYCINE 99% Tioglis Tiopronino Tioproninum Vincol n-(2-mercapto-1-oxopropyl)-glycin [(2-mercaptopropanoyl)amino]acetic acid N-(α-Mercaptopropionyl)glycine SF-572 2-(2-Sulfanylpropanoylamino)acetic acid 2-MPG Thiora N-(.alpha.-Mercaptopropionyl) glycine N-(2-Mercaptopropionyl)glycine, Tiopronin (±)-N-(2-Mercapto-1-oxopropyl)glycine 2-(2-mercaptopropanoylamino)acetic acid 2-(2-sulfanylpropanoylamino)ethanoic acid NSC1907 NSC-1907 Tiopronin USP/EP/BP N-(2-mercaptopropionyl)glyciner Tiopronin 1953-02-2 NSC 1907 Glycine, N-(2-mercapto-1-oxopropyl)- N-(2-MercaptopropionyL Tiopronin (APIs) 2-(2-sulfanylpropanamido)acetic acid 2-[(2-mercapto-1-oxopropyl)amino]acetic acid Tiopronin (base and/or unspecified salts) Tiopronin (Thiola)