BRYOSTATIN 1
- CAS No.
- 83314-01-6
- Chemical Name:
- BRYOSTATIN 1
- Synonyms
- BRYO 1;CS-1164;NSC-339555;BRYOSTATIN;Byrostatin 1;BRYOSTATIN 1;bryostatin1,0;(26R)-Bryostatin 1;Bryostatin 1 - CAS 83314-01-6 - Calbiochem;(1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(Acetyloxy)-1,11,21-trihydroxy-17-[(1R)-1-hydroxyethyl]-5,13-bis(2-Methoxy-2-oxoethylidene)-10,10,26,26-tetraMethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.13,7.111,15]nonacos-8-en-12-y
- CBNumber:
- CB9454936
- Molecular Formula:
- C47H68O17
- Molecular Weight:
- 905.03
- MOL File:
- 83314-01-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/30 15:45:59
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335-H373 |
| Precautionary statements | P271-P280-P312 |
| Hazard Codes | Xn |
| Risk Statements | 68 |
| Safety Statements | 22-24/25-36/37 |
| WGK Germany | 3 |
| RTECS | EH9455000 |
| HS Code | 2932990090 |
| Toxicity | LD50 in mice, rats (mg/kg): 0.038, 0.068 i.v. (Prendiville) |
BRYOSTATIN 1 price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | B7431 | Bryostatin 1 ≥99%, solid | 83314-01-6 | 10μG | ₹22591.78 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 203811 | Bryostatin 1 - CAS 83314-01-6 - Calbiochem A macrocyclic lactone with antitumor properties. | 83314-01-6 | 10μG | ₹18830 | 2022-06-14 | Buy |
BRYOSTATIN 1 Chemical Properties,Uses,Production
Uses
Bryostatin 1 has been used to study its effects on spontaneous Crohn′s disease (CD) like colitis in?mice. It has also been used to study its effects as an anthelmintic drug on adult Syphacia muris infection in rats.
Definition
ChEBI: A member of the class of bryostatins that is (17E)-2-oxooxacyclohexacos-17-ene which is substituted by hydroxy groups at positions 4, 10, and 20; an acetoxy group at position 8; methyl groups at positions 9, 9, 18, and 19; 2-methoxy-2-oxoe hylidene groups at positions 14 and 24; an (E,E)-octa-2,4-dienoyloxy group at position 21; and with oxygen bridges linking positions 6 to 10, 12 to 16, and 20 to 24. It is one of the most abundant member of the class of br ostatins.
Biological Activity
Protein kinase C (PKC) activator that binds with high affinity (K i = 1.35 nM). Initially activates and subsequently induces downregulation of PKC isozymes. Sensitizes tumor cells to cytotoxic effects of anticancer agents.
BRYOSTATIN 1 Preparation Products And Raw materials
Raw materials
Preparation Products
BRYOSTATIN 1 Suppliers
Global( 58)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| BOC Sciences | 16314854226; +16314854226 | United States | 19743 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 52927 | 58 | Inquiry |
| TargetMol Chemicals Inc. | 15002134094 | China | 28118 | 58 | Inquiry |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | China | 7892 | 56 | Inquiry |
| Cayman Chemical Company | (800) 364-9897 | United States | 6618 | 81 | Inquiry |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | China | 9707 | 58 | Inquiry |
83314-01-6(BRYOSTATIN 1)Related Search:
ETHYL (R)-3-HYDROXY-TETRADECANOATE
BRYOSTATIN 2
20-O-Butyryl-20-O-de(1-oxo-2,4-octadienyl)bryostatin 1,Bryostatin 9
bryostatin 18
bryostatin 5
chevron_left
1of4
chevron_right
BRYOSTATIN 1
BRYO 1
BRYOSTATIN
bryostatin1,0
(26R)-Bryostatin 1
NSC-339555
(1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(Acetyloxy)-1,11,21-trihydroxy-17-[(1R)-1-hydroxyethyl]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.13,7.111,15]nonacos-8-en-12-yl2,4-octadienoicacidester
2,4-Octadienoic acid, (1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(acetyloxy)-1,11,21-trihydroxy-17-(1R)-1-hydroxyethyl-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo21.3.1.13,7.111,15nonacos-8-en
(1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(Acetyloxy)-1,11,21-trihydroxy-17-[(1R)-1-hydroxyethyl]-5,13-bis(2-Methoxy-2-oxoethylidene)-10,10,26,26-tetraMethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.13,7.111,15]nonacos-8-en-12-y
Byrostatin 1
CS-1164
(1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(Acetyloxy)-1,11,21-trihydroxy-17-[(1R)-1-hydroxyethyl]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.13,7.111,15]nonacos-8-en-12-yl-(2E, 4E)-2,4-octadienoic acid ester
Bryostatin 1 - CAS 83314-01-6 - Calbiochem
2,4-Octadienoic acid, (1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(acetyloxy)-1,11,21-trihydroxy-17-[(1R)-1-hydroxyethyl]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.13,7.111,15]nonacos-8-en-12-yl ester, (2E,4E)-
83314-01-6
C47H68O1
C47H68O17
Kinase/Phosphatase Biology
Protein Kinase C (PKC)
Serine/Threonine Kinase Activators
Cell Signaling and Neuroscience
Cell Biology
BioChemical
Cell Signaling and Neuroscience
Kinase/Phosphatase Biology
Protein Kinase ActivatorsSerine/Threonine Kinase Biology
Protein Kinase C (PKC)
Serine/Threonine Kinase Activators
inhibitor