BRYOSTATIN 1
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- ₹18830 - ₹22591.78
- Product name: BRYOSTATIN 1
- CAS: 83314-01-6
- MF: C47H68O17
- MW: 905.03
- EINECS:
- MDL Number:MFCD00893832
- Synonyms:BRYOSTATIN 1;BRYO 1;BRYOSTATIN;bryostatin1,0;(26R)-Bryostatin 1;NSC-339555;(1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(Acetyloxy)-1,11,21-trihydroxy-17-[(1R)-1-hydroxyethyl]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.13,7.111,15]nonacos-8-en-12-yl2,4-octadienoicacidester;2,4-Octadienoic acid, (1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(acetyloxy)-1,11,21-trihydroxy-17-(1R)-1-hydroxyethyl-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo21.3.1.13,7.111,15nonacos-8-en
2 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 10μG
- ManufacturerSigma-Aldrich(India)
- Product numberB7431
- Product descriptionBryostatin 1 ≥99%, solid
- Packaging10μG
- Price₹22591.78
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number203811
- Product descriptionBryostatin 1 - CAS 83314-01-6 - Calbiochem A macrocyclic lactone with antitumor properties.
- Packaging10μG
- Price₹18830
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | B7431 | Bryostatin 1 ≥99%, solid | 10μG | ₹22591.78 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 203811 | Bryostatin 1 - CAS 83314-01-6 - Calbiochem A macrocyclic lactone with antitumor properties. | 10μG | ₹18830 | 2022-06-14 | Buy |
Properties
Melting point :230-235°
alpha :D25 +34.1° (c = 0.044 in methanol)
Boiling point :716.44°C (rough estimate)
Density :1.1245 (rough estimate)
refractive index :1.5940 (estimate)
storage temp. :-20°C
solubility :DMSO: soluble
pka :11.10±0.70(Predicted)
form :solid
color :white
optical activity :+34.125 (methanol)
alpha :D25 +34.1° (c = 0.044 in methanol)
Boiling point :716.44°C (rough estimate)
Density :1.1245 (rough estimate)
refractive index :1.5940 (estimate)
storage temp. :-20°C
solubility :DMSO: soluble
pka :11.10±0.70(Predicted)
form :solid
color :white
optical activity :+34.125 (methanol)
Safety Information
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Description
Bryostatin 1 is structurally unique macrolactone marine natural product that binds to and modulates PKC (protein kinase C) activity at picomolar concentrations, but is not a carcinogen or a complete tumor promoter. In many systems it induces only a subset of the responses to PMA and blocks those which it does not induce. It is markedly more potent than PMA for translocating PKCδ and -ε. Animal tests have shown bryostatin 1 may alleviate brain damage after a stroke. Bryostatin 1 administered with lactacystin has displayed synergistically induced apoptosis in human leukemia cells.More related product prices
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