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BRYOSTATIN 1

BRYOSTATIN 1 Structure
  • ₹18830 - ₹22591.78
  • Product name: BRYOSTATIN 1
  • CAS: 83314-01-6
  • MF: C47H68O17
  • MW: 905.03
  • EINECS:
  • MDL Number:MFCD00893832
  • Synonyms:BRYOSTATIN 1;BRYO 1;BRYOSTATIN;bryostatin1,0;(26R)-Bryostatin 1;NSC-339555;(1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(Acetyloxy)-1,11,21-trihydroxy-17-[(1R)-1-hydroxyethyl]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.13,7.111,15]nonacos-8-en-12-yl2,4-octadienoicacidester;2,4-Octadienoic acid, (1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(acetyloxy)-1,11,21-trihydroxy-17-(1R)-1-hydroxyethyl-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo21.3.1.13,7.111,15nonacos-8-en
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 10μG
  • ManufacturerSigma-Aldrich(India)
  • Product numberB7431
  • Product descriptionBryostatin 1 ≥99%, solid
  • Packaging10μG
  • Price₹22591.78
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number203811
  • Product descriptionBryostatin 1 - CAS 83314-01-6 - Calbiochem A macrocyclic lactone with antitumor properties.
  • Packaging10μG
  • Price₹18830
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) B7431 Bryostatin 1 ≥99%, solid 10μG ₹22591.78 2022-06-14 Buy
Sigma-Aldrich(India) 203811 Bryostatin 1 - CAS 83314-01-6 - Calbiochem A macrocyclic lactone with antitumor properties. 10μG ₹18830 2022-06-14 Buy

Properties

Melting point :230-235°
alpha :D25 +34.1° (c = 0.044 in methanol)
Boiling point :716.44°C (rough estimate)
Density :1.1245 (rough estimate)
refractive index :1.5940 (estimate)
storage temp. :-20°C
solubility :DMSO: soluble
pka :11.10±0.70(Predicted)
form :solid
color :white
optical activity :+34.125 (methanol)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.

Description

Bryostatin 1 is structurally unique macrolactone marine natural product that binds to and modulates PKC (protein kinase C) activity at picomolar concentrations, but is not a carcinogen or a complete tumor promoter. In many systems it induces only a subset of the responses to PMA and blocks those which it does not induce. It is markedly more potent than PMA for translocating PKCδ and -ε. Animal tests have shown bryostatin 1 may alleviate brain damage after a stroke. Bryostatin 1 administered with lactacystin has displayed synergistically induced apoptosis in human leukemia cells.

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CLEARSYNTH LABS LTD. Pharmaffiliates Analytics and Synthetics P. Ltd Pharma Affiliates
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Aladdin Scientific TargetMol Chemicals Inc. Sichuan Wei Keqi Biological Technology Co., Ltd. Cayman Chemical Company Shanghai EFE Biological Technology Co., Ltd.