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BRYOSTATIN 1

BRYOSTATIN 1 Structure
  • ₹18830 - ₹22591.78
  • Product name: BRYOSTATIN 1
  • CAS: 83314-01-6
  • MF: C47H68O17
  • MW: 905.03
  • EINECS:
  • MDL Number:MFCD00893832
  • Synonyms:BRYOSTATIN 1;BRYO 1;BRYOSTATIN;bryostatin1,0;(26R)-Bryostatin 1;NSC-339555;(1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(Acetyloxy)-1,11,21-trihydroxy-17-[(1R)-1-hydroxyethyl]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.13,7.111,15]nonacos-8-en-12-yl2,4-octadienoicacidester;2,4-Octadienoic acid, (1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(acetyloxy)-1,11,21-trihydroxy-17-(1R)-1-hydroxyethyl-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo21.3.1.13,7.111,15nonacos-8-en
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 10μG
  • ManufacturerSigma-Aldrich(India)
  • Product numberB7431
  • Product descriptionBryostatin 1 ≥99%, solid
  • Packaging10μG
  • Price₹22591.78
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number203811
  • Product descriptionBryostatin 1 - CAS 83314-01-6 - Calbiochem A macrocyclic lactone with antitumor properties.
  • Packaging10μG
  • Price₹18830
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) B7431 Bryostatin 1 ≥99%, solid 10μG ₹22591.78 2022-06-14 Buy
Sigma-Aldrich(India) 203811 Bryostatin 1 - CAS 83314-01-6 - Calbiochem A macrocyclic lactone with antitumor properties. 10μG ₹18830 2022-06-14 Buy

Properties

Melting point :230-235°
alpha :D25 +34.1° (c = 0.044 in methanol)
Boiling point :716.44°C (rough estimate)
Density :1.1245 (rough estimate)
refractive index :1.5940 (estimate)
storage temp. :-20°C
solubility :DMSO: soluble
pka :11.10±0.70(Predicted)
form :solid
color :white
optical activity :+34.125 (methanol)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.

Description

Bryostatin 1 is structurally unique macrolactone marine natural product that binds to and modulates PKC (protein kinase C) activity at picomolar concentrations, but is not a carcinogen or a complete tumor promoter. In many systems it induces only a subset of the responses to PMA and blocks those which it does not induce. It is markedly more potent than PMA for translocating PKCδ and -ε. Animal tests have shown bryostatin 1 may alleviate brain damage after a stroke. Bryostatin 1 administered with lactacystin has displayed synergistically induced apoptosis in human leukemia cells.

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Suppliers and manufacturers

TargetMol Chemicals Inc.
Bryostatin 1
₹593.00 /10μg
Bryostatin 1 CAS:83314-01-6
CLEARSYNTH LABS LTD. Pharmaffiliates Analytics and Synthetics P. Ltd Pharma Affiliates
TargetMol Chemicals Inc.
BOC Sciences
Aladdin Scientific Sichuan Wei Keqi Biological Technology Co., Ltd. Shanghai EFE Biological Technology Co., Ltd. TargetMol Chemicals Inc.