4-BROMO-A23187

4-BROMO-A23187 Structure
CAS No.
76455-48-6
Chemical Name:
4-BROMO-A23187
Synonyms
4-BR-A23187;4-BROMO-A23187;A23187, 4-BROMO;4-BROMOCALCIMYCIN;4-BROMO-ANTIBIOTIC;CALCIMYCIN, 4-BROMO;4-BROMOCALCIMYCIN A23187;4-BROMO-ANTIBIOTIC A23187;ANTIBIOTIC A-23187, 4-BROMO;4-BROMO-CALCIUM IONOPHORE A23187
CBNumber:
CB9490107
Molecular Formula:
C29H36BrN3O6
Molecular Weight:
602.52
MOL File:
76455-48-6.mol
Modify Date:
2023/6/8 9:02:47

4-BROMO-A23187 Properties

Boiling point 735.4±60.0 °C(Predicted)
Density 1.43±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility ethanol: 20 mg/mL
pka 15.14±0.50(Predicted)
form powder
color yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38
Safety Statements  26-36/37/39-36/37
WGK Germany  3
HS Code  29419090
NFPA 704
0
3 0

4-BROMO-A23187 price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) B7272 4-Bromo-calcium Ionophore A23187 powder 76455-48-6 1MG ₹27755.3 2022-06-14 Buy
Sigma-Aldrich(India) 100107 4-Bromo-calcium Ionophore A23187 Brominated analog of the widely used cation ionophore A23187. Non-fluorescent and therefore suitable for use in the presence of fluorescent or metal-c 76455-48-6 1MG ₹23550 2022-06-14 Buy
Product number Packaging Price Buy
B7272 1MG ₹27755.3 Buy
100107 1MG ₹23550 Buy

4-BROMO-A23187 Chemical Properties,Uses,Production

Chemical Properties

Yellow powder

Uses

4-Bromo-calcium Ionophore A23187 has been used for the activation of Ca2+/calmodulin kinase II (CaMKII) in HeLa cell line. It has also been used as a calcium mobilizer to investigate its effect on superoxide dismutase 1 (SOD1) aggregates in VSC 4.1 cells.

Biochem/physiol Actions

4-Bromo-calcium Ionophore A23187 is a modulator of apoptosis. It inhibits apoptosis in a concentration dependent manner in neutrophils which are aging in vitro and increases the intracellular Ca2+ levels.

4-BROMO-A23187 Preparation Products And Raw materials

Raw materials

Preparation Products

4-BROMO-A23187 Suppliers

Global( 75)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
BOC Sciences 16314854226; +16314854226 United States 19743 58 Inquiry
Shanghai Acmec Biochemical Technology Co., Ltd. +undefined18621343501 China 33350 58 Inquiry
Guangzhou Yaoguang Technology Co., Ltd. 13020159086 China 487 58 Inquiry
RD International Technology Co., Limited 18024082417 China 9155 58 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 China 9708 58 Inquiry
EMD Biosciences, Inc. 858 450 5500 United States 6529 66 Inquiry
Fluorochem Ltd. +44 1457 868921 United Kingdom 6406 74 Inquiry
VWR International 800 932 5000 United Kingdom 6554 82 Inquiry
ANTIBIOTIC A-23187, 4-BROMO CALCIMYCIN, 4-BROMO 4-BROMO-A23187 4-BROMO-ANTIBIOTIC 4-BROMO-ANTIBIOTIC A23187 4-BROMOCALCIMYCIN 4-BROMOCALCIMYCIN A23187 4-BROMO-CALCIUM IONOPHORE A23187 4-BR-A23187 A23187, 4-BROMO 4-BROMO-CALCIUM IONOPHORE A23187FREE ACI D 4-Bromo-A23187, 4-Bromo-calcimycin 6-broMo-5-(MethylaMino)-2-(((2R,3R,6S,8S,9R,11R)-3,9,11-triMethyl-8-((S)-1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl)-1,7-dioxaspiro[5.5]undecan-2-yl)Methyl)benzo[d]oxazole-4-carboxylic acid 4-BroMo A-23187, free acid [4-BroMo-calciuM Ionophore A23187], [Antibiotic A-23187, 4-BroMo] A23187, 4-Bromo- - CAS 76455-48-6 - Calbiochem 4 Bromo A23187,4Bromo A23187,4-Bromo A-23187 4-Benzoxazolecarboxylic acid, 6-bromo-5-(methylamino)-2-[[(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]- 76455-48-6 C29H36BrN3O6 BioChemical Antibiotics Antibiotics A to Z Antibiotics A-F