DEOXYCHOLIC-2,2,4,4-D4 ACID

DEOXYCHOLIC-2,2,4,4-D4 ACID Structure
CAS No.
112076-61-6
Chemical Name:
DEOXYCHOLIC-2,2,4,4-D4 ACID
Synonyms
Deoxycholic acid-D;Deoxycholic-d4 Acid;2H4]-Deoxycholic acid;DEOXYCHOLIC-2,2,4,4-D4 ACID;Deoxycholic acid-2,2,4,4-d4;Deoxycholic Acid-[d4] (Solution);Deoxycholic Acid-d4 MaxSpec? Standard;DEOXYCHOLIC ACID (2,2,4,4-D4, 98%) 100 UG/ML IN METHANOL
CBNumber:
CB9491841
Molecular Formula:
C24H40O4
Molecular Weight:
392.58
MOL File:
112076-61-6.mol
Modify Date:
2023/6/8 9:02:48

DEOXYCHOLIC-2,2,4,4-D4 ACID Properties

Melting point 171-174 °C
Flash point 9℃
storage temp. -20°C
solubility DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly)
form Solid
color White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS06,GHS08
Signal word  Danger
Hazard statements  H225-H301+H311+H331-H370
Precautionary statements  P210-P260-P280-P301+P310+P330-P308+P311-P403+P233
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26-36
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  3
NFPA 704
0
2 0

DEOXYCHOLIC-2,2,4,4-D4 ACID Chemical Properties,Uses,Production

Description

Deoxycholic acid-d4 (DCA-d4) is intended for use as an internal standard for the quantification of DCA (Item Nos. 20756 | 18231) by GC- or LC-MS. DCA is a secondary bile acid that is formed via microbial transformation of cholic acid in the colon. It can be conjugated to glycine or taurine to produce glycodeoxycholic acid (GDCA; ) or taurodeoxycholic acid (TDCA; ), respectively, in hepatocytes. DCA (0.2% v/v) inhibits spore germination induced by taurocholic acid (TCA; ) in seven C. difficile strains, as well as inhibits growth and decreases the cytotoxicity of C. difficile culture supernatants to Vero cells when used at a concentration of 0.02% v/v. It inhibits ionizing radiation-induced p53-dependent transcription in a reporter assay using HCT116 cells when used at a concentration of 200 μM. Fecal and intestinal tissue levels of DCA are increased in a rat model of high-fat diet-induced obesity compared with rats fed a normal diet. Increased serum DCA levels have been found in patients with colorectal cancer.

Uses

Deoxycholic-2,2,4,4-d4 Acid (CAS# 112076-61-6) is a useful isotopically labeled research compound.

DEOXYCHOLIC-2,2,4,4-D4 ACID Preparation Products And Raw materials

Raw materials

Preparation Products

DEOXYCHOLIC-2,2,4,4-D4 ACID Suppliers

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DEOXYCHOLIC-2,2,4,4-D4 ACID Deoxycholic acid-2,2,4,4-d4 Deoxycholic-d4 Acid Deoxycholic acid-D Deoxycholic Acid-[d4] (Solution) DEOXYCHOLIC ACID (2,2,4,4-D4, 98%) 100 UG/ML IN METHANOL Deoxycholic Acid-d4 MaxSpec? Standard 2H4]-Deoxycholic acid 112076-61-6 Steroids & Hormones - 13C & 2H Alphabetical Listings DStable Isotopes Labeled Bioactive Compounds Stable Isotopes Steroids