CHOLIC-2,2,4,4-D4 ACID
- CAS No.
- 116380-66-6
- Chemical Name:
- CHOLIC-2,2,4,4-D4 ACID
- Synonyms
- Cholic-d4 Acid;2H4]-Cholic Acid;Cholic acid-2,2,4,4-d;Cholic Acid -[d4] (Solution);Cholic Acid-d4 MaxSpec? Standard;5β-cholanic acid-3α,7α,12α-triol-2,2,4,4-d4;CHOLIC ACID (2,2,4,4-D4, 98%) 100 UG/ML IN METHANOL
- CBNumber:
- CB0334837
- Molecular Formula:
- C24H36D4O5
- Molecular Weight:
- 412.6
- MOL File:
- 116380-66-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/8 9:03:09
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H370 | |||||||||
| Precautionary statements | P210-P233-P240-P241-P242-P243-P260-P264-P270-P280-P303+P361+P353-P307+P311-P321-P370+P378-P403+P235-P405-P501 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
CHOLIC-2,2,4,4-D4 ACID Chemical Properties,Uses,Production
Description
Cholic acid-d4 is intended for use as an internal standard for the quantification of cholic acid by GC- or LC-MS. Cholic acid is a primary bile acid. It is formed from cholesterol via a multistep process catalyzed by the cytochrome P450 (CYP) isoforms CYP7A1, CYP8B1, and CYP27A1. Cholic acid is conjugated to glycine or taurine by bile acid-CoA:amino acid N-acyltransferase (BAAT) to produce glycocholic acid (GCA; ) and taurocholic acid (TCA; ), respectively, in the liver, and is transformed into the secondary bile acid deoxycholic acid (DCA; ) by intestinal microbiota. It induces C. difficile colony formation in an agar dilution assay when used at a concentration of 0.1% w/v. Dietary administration of cholic acid (0.4% w/w) increases serum cholesterol levels, biliary phospholipid secretion, and fecal DCA levels in rats.
Uses
Cholic Acid-d4 is a labelled analog of Cholic acid (C432600) which is a choleretic produced by, and isolated from liver cells.
CHOLIC-2,2,4,4-D4 ACID Preparation Products And Raw materials
Raw materials
Preparation Products
CHOLIC-2,2,4,4-D4 ACID Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-400-6206333 18521732826 | China | 25009 | 65 | Inquiry |
| Nantong Hanfang Biotechnology Co. , Ltd. | 18616537568 | China | 30968 | 58 | Inquiry |
| Nanjing Shizhou Biology Technology Co.,Ltd | 17301488900 | China | 12582 | 58 | Inquiry |
| Shanghai klamar Reagent Co., LTD | 4001650900 13817534909 | China | 10710 | 58 | Inquiry |
| SHANGHAI ZZBIO CO., LTD. | 15102117276 19921389125 | China | 12064 | 58 | Inquiry |
| PureChemland Co.,Ltd. | 19936016343 | China | 3541 | 58 | Inquiry |
| ChengDu SinoStandards Bio-Tech Co.,Ltd. ， | 028-83243028 19136088901 | China | 4986 | 58 | Inquiry |
| Riedel-de Haen AG | 800 558-9160 | United States | 6825 | 87 | Inquiry |