B-HT 933 DIHYDROCHLORIDE

B-HT 933 DIHYDROCHLORIDE Structure
CAS No.
36067-72-8
Chemical Name:
B-HT 933 DIHYDROCHLORIDE
Synonyms
b-ht933;Nsc310831;Azepexole hydrochloride;B-HT 933 (hydrochloride);Azepexole dihydrochloride;β2AR/M3-receptor agonist-1;B-HT 933 DIHYDROCHLORIDE SELECTIVE A2 AD RENORE;5-d)azepin-2-amine,5,6,7,8-tetrahydro-6-ethyl-4h-oxazolo(dihydrochloride;5,6,7,8-tetrahydro-6-ethyl-4h-oxazolo(4,5-d)azepin-2-aminedihydrochloride;2-amino-6-ethyl-4,5,7,8-tetrahydro-6h-oxazolo(5,4-d)azepinedihydrochloride
CBNumber:
CB9496972
Molecular Formula:
C9H16ClN3O
Molecular Weight:
217.7
MOL File:
36067-72-8.mol
Modify Date:
2023/6/30 15:45:59

B-HT 933 DIHYDROCHLORIDE Properties

storage temp. Desiccate at RT
solubility H2O: >20 mg/mL
form solid
color white to off-white

SAFETY

Risk and Safety Statements

WGK Germany  2
RTECS  RQ5831345

B-HT 933 DIHYDROCHLORIDE Chemical Properties,Uses,Production

Description

B-HT 933 is an agonist of α2-adrenergic receptors (α2-ARs) with an EC50 value of 0.65 μM for contraction of canine sapheneous veins. It induces concentration-dependent inhibition of the twitch response in rat vas deferens and guinea pig ileum. B-HT 933 induces sedation and reduces motor activity in mice, an effect that is reversed by the α2-AR antagonist yohimbine . B-HT 933 decreases blood pressure and cardiac output in cats injected with 30 μg/kg intracisternally. It also exhibits antinociceptive effects in mice with ED50 values of 12.5, 20.5, and 6.1 mg/kg for the tail-immersion, tail-pinch, and acetic acid writhing tests, respectively.

Uses

B-HT 933 Dihydrochloride is a selective α2-adrenoceptor agonist and has less potent inhibitory effect on the sympathetic vasopressor responses in diabetic rats.

B-HT 933 DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

B-HT 933 DIHYDROCHLORIDE Suppliers

Global( 21)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
RD International Technology Co., Limited 18024082417 China 9155 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 24017 58 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 China 9708 58 Inquiry
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 China 4398 58 Inquiry
Beijing Hassanal Technology Limited Liability Company 010-8293620852266225 China 750 43 Inquiry
CHEMICAL LAND21 82- 2 -783 - 8063 South Korea 6315 74 Inquiry
SIGMA-RBI 800 736 3690 (Orders) Switzerland 6913 91 Inquiry
2-amino-6-ethyl-4,5,7,8-tetrahydro-6h-oxazolo(5,4-d)azepinedihydrochloride 5,6,7,8-tetrahydro-6-ethyl-4h-oxazolo(4,5-d)azepin-2-aminedihydrochloride 5-d)azepin-2-amine,5,6,7,8-tetrahydro-6-ethyl-4h-oxazolo(dihydrochloride b-ht933 B-HT 933 DIHYDROCHLORIDE SELECTIVE A2 AD RENORE Azepexole dihydrochloride, 6-Ethyl-5,6,7,8-tetrahydro-4H-oxazolo[4,5-d]azepin-2-amine dihydrochloride Azepexole hydrochloride Nsc310831 Azepexole dihydrochloride B-HT 933 (hydrochloride) β2AR/M3-receptor agonist-1 36067-72-8 C9H15N3O2HCl