B-HT 933 DIHYDROCHLORIDE
- CAS No.
- 36067-72-8
- Chemical Name:
- B-HT 933 DIHYDROCHLORIDE
- Synonyms
- b-ht933;Nsc310831;Azepexole hydrochloride;B-HT 933 (hydrochloride);Azepexole dihydrochloride;β2AR/M3-receptor agonist-1;B-HT 933 DIHYDROCHLORIDE SELECTIVE A2 AD RENORE;5-d)azepin-2-amine,5,6,7,8-tetrahydro-6-ethyl-4h-oxazolo(dihydrochloride;5,6,7,8-tetrahydro-6-ethyl-4h-oxazolo(4,5-d)azepin-2-aminedihydrochloride;2-amino-6-ethyl-4,5,7,8-tetrahydro-6h-oxazolo(5,4-d)azepinedihydrochloride
- CBNumber:
- CB9496972
- Molecular Formula:
- C9H16ClN3O
- Molecular Weight:
- 217.7
- MOL File:
- 36067-72-8.mol
- Modify Date:
- 2023/6/30 15:45:59
B-HT 933 DIHYDROCHLORIDE Chemical Properties,Uses,Production
Description
B-HT 933 is an agonist of α2-adrenergic receptors (α2-ARs) with an EC50 value of 0.65 μM for contraction of canine sapheneous veins. It induces concentration-dependent inhibition of the twitch response in rat vas deferens and guinea pig ileum. B-HT 933 induces sedation and reduces motor activity in mice, an effect that is reversed by the α2-AR antagonist yohimbine . B-HT 933 decreases blood pressure and cardiac output in cats injected with 30 μg/kg intracisternally. It also exhibits antinociceptive effects in mice with ED50 values of 12.5, 20.5, and 6.1 mg/kg for the tail-immersion, tail-pinch, and acetic acid writhing tests, respectively.
Uses
B-HT 933 Dihydrochloride is a selective α2-adrenoceptor agonist and has less potent inhibitory effect on the sympathetic vasopressor responses in diabetic rats.
B-HT 933 DIHYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
B-HT 933 DIHYDROCHLORIDE Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Aladdin Scientific | +1-+1(833)-552-7181 | United States | 52927 | 58 | Inquiry |
RD International Technology Co., Limited | 18024082417 | China | 9155 | 58 | Inquiry |
TargetMol Chemicals Inc. | 4008200310 | China | 24017 | 58 | Inquiry |
Cayman Chemical Company | (800) 364-9897 | United States | 6618 | 81 | Inquiry |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | China | 9708 | 58 | Inquiry |
Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | China | 4398 | 58 | Inquiry |
Beijing Hassanal Technology Limited Liability Company | 010-8293620852266225 | China | 750 | 43 | Inquiry |
CHEMICAL LAND21 | 82- 2 -783 - 8063 | South Korea | 6315 | 74 | Inquiry |
SIGMA-RBI | 800 736 3690 (Orders) | Switzerland | 6913 | 91 | Inquiry |