ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Piperazine compounds >trans-1-Cinnamylpiperazine

trans-1-Cinnamylpiperazine

trans-1-Cinnamylpiperazine Structure
CAS No.
87179-40-6
Chemical Name:
trans-1-Cinnamylpiperazine
Synonyms
TIMTEC-BB SBB000411;N-CINNAMYLPIPERAZINE;1-(CINNAMYL)PIPERAZINE;LABOTEST-BB LT00233225;Flunarizine Impurity 9;trans-1-Ciamylpiperazine;(E)-1-Cinnamylpiperazine;TRANS-1-CINNAMYLPIPERAZINE;1-TRANS-CINNAMYL PIPERAZINE;1-(3-PHENYL-ALLYL)-PIPERAZINE
CBNumber:
CB9737918
Molecular Formula:
C13H18N2
Molecular Weight:
202.3
MOL File:
87179-40-6.mol
Modify Date:
2024/3/28 10:29:10

trans-1-Cinnamylpiperazine Properties

Melting point 39-44 °C(lit.)
Boiling point 129 °C1 mm Hg(lit.)
Density 0.989 g/mL at 25 °C(lit.)
refractive index 1.574-1.576
Flash point >230 °F
storage temp. Refrigerator, under inert atmosphere
solubility Chloroform (Sparingly), Methanol (Slightly)
pka 9.17±0.10(Predicted)
form Solid
color Pale Yellow
BRN 608984
InChI InChI=1S/C13H18N2/c1-2-5-13(6-3-1)7-4-10-15-11-8-14-9-12-15/h1-7,14H,8-12H2/b7-4+
InChIKey WGEIOMTZIIOUMA-QPJJXVBHSA-N
SMILES N1(C/C=C/C2=CC=CC=C2)CCNCC1
CAS DataBase Reference 87179-40-6(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338-P280a-P304+P340-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
HS Code  29335995
NFPA 704
1
2 0

trans-1-Cinnamylpiperazine Chemical Properties,Uses,Production

Description

trans-1-Cinnamylpiperazine is a piperazine derivative. It was used as a test compound to investigate the in vitro efficacy as an antiprotozoal against Philasterides dicentrarchi. It may be used to synthesize Incentrom A derivatives.

Chemical Properties

clear colorless to yellow liquid

Uses

trans-1-Cinnamylpiperazine is used in the synthesis of bile acid piperazinyl derivatives which display pro-apoptotic properties on carcinoma human cell lines.

General Description

trans-1-Cinnamylpiperazine is a piperazine derivative.

General Description

trans-1-Cinnamylpiperazine is an important organic synthetic reagent for the preparation of opioid tripeptides hybridised with trans-1-Cinnamylpiperazine, which exhibits low haematotoxicity and good cancer cell growth as an inhibitor of pancreatic cancer cell proliferation in two- and three-dimensional in vitro models Inhibition. It was also used in the preparation of the anticonvulsant active substance cinnamylpiperazine derivatives.

trans-1-Cinnamylpiperazine Preparation Products And Raw materials

Raw materials

Preparation Products

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N-CINNAMYLPIPERAZINE TRANS-1-CINNAMYLPIPERAZINE TIMTEC-BB SBB000411 LABOTEST-BB LT00233225 1-TRANS-CINNAMYL PIPERAZINE 1-(3-PHENYL-ALLYL)-PIPERAZINE 1-(CINNAMYL)PIPERAZINE 1-((E)-3-PHENYLALLYL)PIPERAZINE trans-1-Cinnamylpiperazine,97% 1-Phenyl-3-(1-piperazino)-1-propene trans-1-Ciamylpiperazine 1-(3-phenyl-2-propenly)piperazine trans-1-Cinnamylpiperazine 97% N-Cinnamyl piperazine 1-Cinnamylpiperazine trans-1-CinnaMylpiperazine hydrochloride Flunarizine Impurity 9 Piperazine, 1-[(2E)-3-phenyl-2-propen-1-yl]- (E)-1-(3-Phenyl-2-propenyl)piperazine TRANS-1-CINNAMYLPIPERAZINE 87179-40-6 trans-1-Cinnamylpiperazine ISO 9001:2015 REACH (E)-1-Cinnamylpiperazine 1-(3-Phenylprop-2-en-1-yl)piperazine, trans Bucinnazine hydrochloride Impurity 6 Bucinnazine Hydrochloride ImpuritⅠ:(E)-1-(3-Phenyl-2-propenyl)piperazine 1-(3-phenyl-2-propenly)piperazine (HCL) Bucinnazine Hydrochloride ImpuritⅠ:(E)-1-(3-Phenyl-2-propenyl)piperazine Flunarizine Impurity 15 Dihydrochloride 87179-40-6 Building Blocks Heterocyclic Building Blocks Piperazines Heterocyclic Building Blocks Piperazines Piperaizine Building Blocks