C6 CERAMIDE
- CAS No.
- 124753-97-5
- Chemical Name:
- C6 CERAMIDE
- Synonyms
- C6 CERAMIDE;CERAMIDE C6;06:0 CERAMIDE;CAPROYL CERAMIDE;C8 SPHINGOID BASE;C6-D-ERYTHRO-CERAMIDE;N-HEXANOYLSPHINGOSINE;C6 Ceramide (d18:1/6:0);N-CAPROYL-D-SPHINGOSINE;N-HEXANOY-D-SPHINGOSINE
- CBNumber:
- CB9744617
- Molecular Formula:
- C24H47NO3
- Molecular Weight:
- 397.63
- MOL File:
- 124753-97-5.mol
- Modify Date:
- 2024/4/26 17:21:34
| Melting point | 76-77°C |
|---|---|
| Boiling point | 521.03°C (rough estimate) |
| Density | 1.0077 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | -20°C |
| solubility | Soluble in 100% ethanol at 25mg/ml and also in DMSO at 50mg/ml. |
| pka | 13.53±0.20(Predicted) |
| form | Powder |
| color | White |
| Stability | Freezer -20°C |
| LogP | 7.463 (est) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P280-P261-P271 |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| HS Code | 29241990 |
C6 CERAMIDE price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | H6524 | N-Hexanoyl-D-sphingosine ≥98% (TLC), synthetic | 124753-97-5 | 1MG | ₹2771.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | H6524 | N-Hexanoyl-D-sphingosine ≥98% (TLC), synthetic | 124753-97-5 | 5MG | ₹8313.6 | 2022-06-14 | Buy |
| Sigma-Aldrich | 376650 | D-erythro-Sphingosine, N-Hexanoyl- - CAS 124753-97-5 - Calbiochem Biologically active, cell-permeable, non-physiological ceramide analog. | 124753-97-5 | 5MG | ₹14100 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 376650 | D-erythro-Sphingosine, N-Hexanoyl- - CAS 124753-97-5 - Calbiochem Biologically active, cell-permeable, non-physiological ceramide analog. | 124753-97-5 | 5MG | ₹14100 | 2022-06-14 | Buy |
C6 CERAMIDE Chemical Properties,Uses,Production
Description
C6 ceramide is a cell-permeable analog of naturally occurring ceramides. With a longer carbon chain than C2 ceramide, it is somewhat more hydrophobic, and may more closely mimic the effects of natural ceramides. C6 ceramide mediates many diverse biological activities including apoptosis, activation of protein phosphatase 2A, and inhibition of the mitochondrial respiratory chain. It also enhances the expression of COX-2 in rat granulosa cells and stimulates the growth of bovine aortic smooth muscle cells. C6 ceramide acts in neuronal axons to inhibit neurite growth.
Chemical Properties
Off White Powder
Uses
C6 Ceramide (d18:1/6:0) has been used as a chemotherapeutic agent to test its anti-tumor effect in breast cancer cells and ovarian cancer cell lines. It has also been used to test chemo-sensitization effects in cancer cells.
General Description
Biologically active, cell-permeable, non-physiological ceramide analog. Induces a dramatic arrest in the G0/G1 phase of the cell cycle. Activates MAP kinase. Activates protein phosphatase 2A (PP2A) at 10 nM. Inhibits diacylglycerol accumulation and phospholipase D (PLD) activation in fibroblasts. Induces apoptosis in MOLT-4 leukemia cells.
C6 CERAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
C6 CERAMIDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| BINBO BIOLOGICAL CO.,LTD | +8618629063126 | China | 346 | 58 | Inquiry |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | China | 10312 | 58 | Inquiry |
| Alfa Chemistry | United States | 24072 | 58 | Inquiry | |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | China | 33350 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
| Puripharm Co., Ltd. | 0572-2745768-1 13167223168 | China | 299 | 65 | Inquiry |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-400-6206333 18521732826 | China | 25013 | 65 | Inquiry |
| SHANGHAI ZZBIO CO., LTD. | 13916577892 19921389125 | China | 12063 | 58 | Inquiry |
| Shanghai Easy CDMO Co.,Ltd | 021-61734564 | China | 10010 | 58 | Inquiry |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | China | 41844 | 58 | Inquiry |
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