D-ERYTHRO-SPHINGOSINE
![D-ERYTHRO-SPHINGOSINE Structure](CAS/GIF/123-78-4.gif)
- CAS No.
- 123-78-4
- Chemical Name:
- D-ERYTHRO-SPHINGOSINE
- Synonyms
- SPHINGOSINE;D-SPHINGOSINE;Sphingosine (d18:1);CEREBROSIDE;Sphingenine;SPHINGOSINE, D-ERYTHRO;(2S,3R,E)-2-aMinooctadec-4-ene-1,3-diol;BRAIN, BOVINE;4-SPHINGENINE;D-Sphingenine
- CBNumber:
- CB1262764
- Molecular Formula:
- C18H37NO2
- Molecular Weight:
- 299.49
- MOL File:
- 123-78-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/4/25 18:08:01
Melting point | 74.2-78.1 °C |
---|---|
Boiling point | 440.8°C (rough estimate) |
Density | 0.9758 (rough estimate) |
refractive index | 1.5000 (estimate) |
storage temp. | -20°C |
solubility | chloroform: 20 mg/mL, clear, colorless to very faintly yellow |
pka | 11.80±0.45(Predicted) |
form | Powder or Waxy Solid |
color | White to cream |
Merck | 14,8747 |
BRN | 1727294 |
Stability | Stable. Incompatible with strong acids, strong bases, strong oxidizing agents. |
InChIKey | WWUZIQQURGPMPG-KRWOKUGFSA-N |
CAS DataBase Reference | 123-78-4 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P271-P280 | |||||||||
Safety Statements | 22-24/25 | |||||||||
WGK Germany | 3 | |||||||||
F | 1-8-10 | |||||||||
HS Code | 29221985 | |||||||||
NFPA 704 |
|
D-ERYTHRO-SPHINGOSINE price More Price(6)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | S7049 | D-Sphingosine synthetic | 123-78-4 | 5MG | ₹12004.93 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | S7049 | D-Sphingosine synthetic | 123-78-4 | 25MG | ₹32464.18 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 567726 | D-erythro-Sphingosine, Free Base, High Purity - CAS 123-78-4 - Calbiochem Highly purified preparation of bovine brain sphingosine containing >99% of the erythro isomer. | 123-78-4 | 10MG | ₹14260 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 44066 | D-Sphingosine ≥98.0% (TLC) | 123-78-4 | 50MG | ₹27365.6 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 44066 | D-Sphingosine ≥98.0% (TLC) | 123-78-4 | 250MG | ₹108498.98 | 2022-06-14 | Buy |
D-ERYTHRO-SPHINGOSINE Chemical Properties,Uses,Production
Chemical Properties
White Crystalline Solid
Uses
D-erythro-Sphingosine is used to inhibits protein kinase C and calmodulin-dependent enzymes, induces apoptosis. And also used to constituent of cell membranes.
Definition
cerebroside: Any one of a class ofglycolipids in which a single sugarunit is bound to a sphingolipid. The most commoncerebrosides are galactocerebrosides,containing the sugar group galactose;they are found in the plasma membranesof neural tissue and are abundantin the myelin sheaths ofneurones.
General Description
Sphingosine (d18:1) is a spingoid base present in plant and animals. It has 2-amino-1,3-diol functionality and its extraction from animal tissue is laborious. Sphingosine (d18:1) synthesis is performed by chirospecific method using D-galactose.
Biological Activity
Inhibitor of protein kinase C and calmodulin-dependent enzymes, but may stimulate mast cells by activation of protein kinase C.
Purification Methods
D-Sphingosine is purified by recrystallisation from EtOAc, Et2O or pet ether (60-80o). It is insoluble in H2O but is soluble in Me2CO, EtOH and MeOH. It has IR bands at 1590 and 875 cm-1, and is characterised as the tribenzoate m 122-123o (from 95% EtOH). [Tipton Biochemical Preparations 9 127 1962.]
D-ERYTHRO-SPHINGOSINE Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | China | 12456 | 58 | Inquiry |
BINBO BIOLOGICAL CO.,LTD | +8618629063126 | China | 346 | 58 | Inquiry |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21669 | 55 | Inquiry |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29898 | 58 | Inquiry |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | China | 10312 | 58 | Inquiry |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | China | 8822 | 58 | Inquiry |
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