DILEVALOL

DILEVALOL Structure
CAS No.
75659-07-3
Chemical Name:
DILEVALOL
Synonyms
Levadil;Unicard;Dilevaol;Dilevalon;Sch-19927;DILEVALOL;Dilevalolum;DILEVALOL HCL;(R,R)-Labetalol;Dilevalolum [latin]
CBNumber:
CB9773028
Molecular Formula:
C19H24N2O3
Molecular Weight:
328.41
MOL File:
75659-07-3.mol
Modify Date:
2023/5/4 17:34:42

DILEVALOL Properties

Boiling point 552.7±50.0 °C(Predicted)
Density 1.200±0.06 g/cm3(Predicted)
pka 8.21±0.31(Predicted)

DILEVALOL Chemical Properties,Uses,Production

Description

Dilevalol is a "dual-mechanism" antihypertensive reportedly suitable for a wide range of patients. Its partial beta2-agonist action is expected to induce vasodilation, whereas its beta1-antagonist component may protect against stress-induced hemodynamic charges without altering the cardiac output. Dilevalol is the R,R-isomer of labetalol.

Uses

Specific competitive antagonist at both α-and β-adrenergic receptor sites. Antihypertensive.

World Health Organization (WHO)

Dilevalol, a beta-adrenoreceptor antagonist, was introduced into medicine in 1989 for the treatment of hypertension. Shortly afterwards, its use became associated with isolated cases of hepatic toxicity. Although few cases were reported, the manufacturer discontinued sales in Japan and Portugal, the only countries where the drug was marketed, and withdrew applications for registration elsewhere.

DILEVALOL Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 19)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
QUALITY CONTROL SOLUTIONS LTD. 13670046396 China 18865 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 23963 58 Inquiry
Shanghai Hekang Biotechnology Co., Ltd. 18939837085 China 1824 55 Inquiry
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 China 56070 58 Inquiry
AK Scientific, Inc. 650 494 8666 United States 6357 65 Inquiry
Service Chemical Inc. 888-895-6920 Germany 6373 71 Inquiry
2-Hydroxy-5-[(R)-1-hydroxy-2-[[(R)-1-methyl-3-phenylpropyl]amino]ethyl]benzamide Sch-19927 (-)-5-((1R)-1-Hydroxy-2-((1R)-1-methyl-3-phenylpropylamino)ethyl)salicylamid [iupac] (R,R)-Labetalol 2-Hydroxy-5-((1R)-1-hydroxy-2-(((1R)-1-methyl-3-phenylpropyl)amino)ethyl)benzamide Benzamide, 2-hydroxy-5-((1R)-1-hydroxy-2-(((1R)-1-methyl-3-phenylpropyl)amino)ethyl)- DILEVALOL DILEVALOL HCL Dilevaol Dilevalon Levadil Unicard 2-Hydroxy-5-((R)-1-hydroxy-2-(((R)-4-phenylbutan-2-yl)aMino)ethyl)benzaMide Benzamide, 2-hydroxy-5-(1-hydroxy-2-((1-methyl-3-phenylpropyl)amino)ethyl)-, (R-(R*,R*))- Dilevalolum Dilevalolum [latin] 75659-07-3 Amines Aromatics Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals