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Synephrine

Synephrine Structure
CAS No.
94-07-5
Chemical Name:
Synephrine
Synonyms
oxedrine;p-synephrine;4-(1-hydroxy-2-(methylamino)ethyl)phenol;SYNEPHERINE;1-[4-HYDROXYPHENYL]-2-METHYLAMINOETHANOL;s38537-9;simpalon;simpatol;synefrin;94-07-5-
CBNumber:
CB1129621
Molecular Formula:
C9H13NO2
Molecular Weight:
167.21
MOL File:
94-07-5.mol
MSDS File:
SDS
Modify Date:
2024/8/21 22:41:43

Synephrine Properties

Melting point 187 °C (dec.)(lit.)
Boiling point 295.79°C (rough estimate)
Density 1.1222 (rough estimate)
refractive index 1.4680 (estimate)
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Slightly, Sonicated)
form Solid
pka pKa 9.60±0.02(H2O t = 25.0±0.5 I = 0.01)(Approximate)
color White to Off-White
Merck 14,9012
Stability Hygroscopic
InChI InChI=1/C9H13NO2/c1-10-6-9(12)7-2-4-8(11)5-3-7/h2-5,9-12H,6H2,1H3/t9-/s3
InChIKey YRCWQPVGYLYSOX-DJEYLCQNNA-N
SMILES C1(=CC=C(O)C=C1)[C@@H](O)CNC |&1:7,r|
LogP -0.450
CAS DataBase Reference 94-07-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  DO7350000
HS Code  29225090
NFPA 704
0
2 0

Synephrine price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) S0752 (±)-Synephrine ≥98% 94-07-5 5G ₹6841.4 2022-06-14 Buy
Sigma-Aldrich(India) 75256 Synephrine analytical standard 94-07-5 50MG ₹21444.33 2022-06-14 Buy
TCI Chemicals (India) S0232 Synephrine 94-07-5 5G ₹7000 2022-05-26 Buy
TCI Chemicals (India) S0232 Synephrine 94-07-5 25G ₹21400 2022-05-26 Buy
ottokemi S 2801 (±)-Synephrine 98% 94-07-5 5gm ₹6210 2022-05-26 Buy
Product number Packaging Price Buy
S0752 5G ₹6841.4 Buy
75256 50MG ₹21444.33 Buy
S0232 5G ₹7000 Buy
S0232 25G ₹21400 Buy
S 2801 5gm ₹6210 Buy

Synephrine Chemical Properties,Uses,Production

Chemical Properties

Synephrine, also known as Analeptin or p-synephrine, is naturally occurring alkaloid. It is an off-white to beige powder that is derived from the fruit of small citrus trees (Citrus aurantium). It is soluble in water, insoluble in ether, almost insoluble in chloroform, ether. Synephrine is related structurally to endogenous neurotransmitters (adrenaline and noradrenaline), and acts on several adrenergic and serotonergic receptors.

Uses

(±)-Synephrine has been used as an alkaloid to investigate its in vitro antiviral, antibacterial, antifungal and cytotoxicity activities.

Definition

ChEBI: Synephrine is a phenethylamine alkaloid that is 4-(2-aminoethyl)phenol substituted by a hydroxy group at position 1 and a methyl group at the amino nitrogen. It has a role as a plant metabolite and an alpha-adrenergic agonist. It is a phenethylamine alkaloid, a member of phenols and a member of ethanolamines. It is a conjugate base of a synephrinium.

Application

Synephrine is a α-adrenergic receptor agonist, vasoconstrictor that has been reported to have thermogenic properties. Therefore, it is widely used as a dietary supplement to enhance energy and promote weight loss. It is reported that the (-)-form of synephrine has more potent than that of the (+)-form. (The product is for research purpose only.)

General Description

Synephrine is a sympathomimetic amine from the plant?Citrus aurantium and is identified as a major active component of dietary supplements.

Synephrine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 466)Suppliers
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Ambe Phytoextracts Private Limited +91-1143764376 +91-1143764376 New Delhi, India 37 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
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Clearsynth Labs 91-22-45045900 Maharashtra, India 3889 58 Inquiry
Ambe Phytoextracts Private Limited 08069023792Ext 875 Delhi, India 18 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Sanvin Group of Companies 91-22-61066600 Maharashtra, India 16 58 Inquiry
Otto Chemie Pvt. Ltd. +91 9820041841 Mumbai, India 5873 58 Inquiry
(+/-)-SYNEPHRINE SYNEPHRINE 4-hydroxy-alpha-(methylaminomethyl)benzyl alcohol AKOS NCG1-0008 AURORA KA-6561 DL-SYNEPHRINE 1-(4-hydroxyphenyl)-n-methylethanolamine 4-hydroxy-alpha-((methylamino)methyl)benzenemethanol alpha-(4-oxyphenyl)alpha-oxy-beta-methylaminoaethan analeptin p-Hydroxy-a-[(methylamino)methyl]benzyl alcohol 4-Hdroxy-alpha-(methylaminomethyl)benzyl alcohol (±)-Synephrine,1-(4-Hydroxyphenyl)-2-methylaminoethanol, 4-Hydroxy-α-(methylaminomethyl)benzyl alcohol 4-Hydroxy-α-(methylaminomethyl)benzyl alcohol rac-Synephrine Synephrine (Oxedrine) Oxedrine, BAN Synephrine SynonyMs 1-(4-Hydroxyphenyl)-2-(MethylaMino)ethanol Benzenemethanol, 4-hydroxy-α-[(methylamino)methyl]- Synephrine 1-(4-Hydroxyphenyl)-2-(methylamino)ethanol beta-methylamino-alpha-(4-hydroxyphenyl)ethylalcohol ethaphene methylaminomethyl(4-hydroxyphenyl)carbinol parakorper parasympatol pentedrin p-hydroxy-alpha-((methylamino)methyl)-benzylalcoho p-hydroxy-alpha-((methylamino)methyl)benzylalcohol p-hydroxyphenylmethylaminoethanol p-methylaminoethanolphenol p-oxedrine s38537-9 simpalon simpatol sympathol synefrin synephrin synthenate 4-Hydroxy-α-[[methylamino] methyl] benzenemethanol p-Hydroxy-α-[[methylamino] methyl] benzyl alcohol Benzenemethanol, 4-hydroxy-.alpha.-(methylamino)methyl- SYNEPHRINE BASE PARA-SYNEPHRINE SYNEPHRINE 98+% HPLC FROM CITRUS AURANTIUM L. Synephrine (base and/or unspecified salts) Citrus aurantium P.E.95.0% Synephrine 4-Hydroxy-a-[(methylamino)methyl]benzenemethanol Sympathol ,Oxedrine 1-(4-Hydroxyphenyl)-2-methylaminoethanol, 4-Hydroxy-α-(methylaminomethyl)benzyl alcohol (+/-)-N-Methyloctopamine 4-Hydroxy-a-(methylaminomethyl)benzyl alcohol b-Methylamino-a-(4-hydroxyphenyl)ethyl alcohol Synephrine, 98%, from Citrus aurantium L. Benzenemethanol, 4-hydroxy-a-[(methylamino)menthyl] Synephrine CAS NO.94-07-5 4-[(1S)-1-hydroxy-2-(methylamino)ethyl]phenol Synephrine/Synephrine base Synephrine 95-98%