(2R,5R)-5-Hydroxy-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester

(2R,5R)-5-Hydroxy-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester Structure
CAS No.
147126-62-3
Chemical Name:
(2R,5R)-5-Hydroxy-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester
Synonyms
(2R,5R)-5-Hydroxy-[1,3]-oxathiolane-2-carboxylic acid menthyl ester (HME);Menthyloxathiolane;Lamivudine Impurity 8;Lamivudine Impurity 17;Lamivudine Impurity 40;(2R,5R)-(1R,2S,5R)-2-isopropyl;(1R,2S,5R)-Lamivudine Impurity 32;(1R,2S,5R)-Methyl-5R-hydroxy-[1,3]-oxathiolane-2R-carboxylate;(1R,2S,5R)-Menthol-5R-hydroxy-[1,3]-oxathiolane-2R-carboxylate;(2S,5R)-5-Hydroxy-[1,3]-oxathiolane-2-carboxylic acid menthy...
CBNumber:
CB9788253
Molecular Formula:
C14H24O4S
Molecular Weight:
288.4
MOL File:
147126-62-3.mol
MSDS File:
SDS
Modify Date:
2023/5/4 15:13:00

(2R,5R)-5-Hydroxy-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester Properties

Melting point 99-1010C
Boiling point 402.3±45.0 °C(Predicted)
Density 1.16
vapor pressure 3.53-4.14Pa at 30-50℃
storage temp. Sealed in dry,2-8°C
pka 11.84±0.40(Predicted)
form Powder
LogP 3.18
Dissociation constant 7.36 at 22℃

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302+H332-H412
Precautionary statements  P273-P501

(2R,5R)-5-Hydroxy-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester Chemical Properties,Uses,Production

Chemical Properties

White To Off-White Solid

Uses

Lamivudine (L172500) intermediate.

(2R,5R)-5-Hydroxy-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl(2R,5R)-5-hydroxy-1,3-oxathiolane-2-carboxylate (2R,5R)-5-Hydroxy-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester (2R, 5R)-5-HYDROXY-1,3-OXATHIOLANE-2-CARBOXYLIC ACID METHYL ESTER [1R-[1a(2R*,5R*),2b,5a]]-5-Hydroxy-1,3-Oxathiolane-2-carboxylic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester (2S,5R)-5-Hydroxy-[1,3]-oxathiolane-2-carboxylic acid menthyl ester (HME) (2R, 5R)-5-HYDROXY-1,3-OXATHIOLANE-2-CARBOXYLIC ACID L METHYL ESTER (2S,5R)-5-Hydroxy-[1,3]-oxathiolane-2-carboxylic acid menthyl ester (1R,2S,5R)-Methyl-5R-hydroxy-[1,3]-oxathiolane-2R-carboxylate 5-Hydroxy-[1,3]oxathiolane-2-carboxylic acid 2-isopropyl-5-Methyl-cyclohexyl ester (2R,5R)-5-Hydroxy[1,3]oxathiolane-2-carboxylic Acid L-Methyl Ester, (1R,2S,5R)-Methyl-5R-hydroxy Acid 2-Isopropyl-5-Methyl-cyclohexyl Ester (1R,2S,5R)-Menthol-5R-hydroxy-[1,3]-oxathiolane-2R-carboxylate 1,3-Oxathiolane-2-carboxylic acid, 5-hydroxy-, (1R,2S,5R)-5-Methyl-2-(1-Methylethyl)cyclohexyl ester, (2R,5R)- (2R,5R)-(1R,2S,5R)-2-isopropyl-5-Methylcyclohexyl 5-hydroxy-1,3-oxathiolane-2-carboxylate (2R,5R)-5-Hydroxy-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-Methyl-2-(1-Methylethyl)cyclohexyl (2R,5R)-5-Hydroxy[1,3]oxathiolane-2-carboxylic Acid L-Menthol Ester (2R,5R)-5-Hydroxy-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester (2R, 5R)-5-HYDROXY-1,3-OXATHIOLANE-2-CARBOXYLIC ACID METHYL ESTER [1R-[1a(2R*,5R*),2b,5a]]-5 (2R,5R)-5-HYDROXY-1,3-OXATHIOLANE-2-CARBOXYLIC ACID(1R,2S,5R )-5-METHYL-2-(1-METHYLETHYL)CYCLOHEXYL ESTER (2R,5R)-(1R,2S,5R)-2-isopropyl 5-hydroxy-1,3-oxathiolane-2-carboxylic acid (5-methyl-2-propan-2-ylcyclohexyl) ester Lamivudine Impurity 17 Lamivudine Impurity 8 (2R)-5-Hydroxy-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester (2R,5R)-5-HYDROXY-1,3-OXATHIOLANE-2-CARBOXYLIC ACID MENTHYL ESTE (2R, 5R)-5-Hydroxy-[1, 3]-oxathiolane-2-Carboxylic acid, 2S isopropyl-5r-methyl-1R cyclohexyl ester (ECE) (2S,5R)-5-Hydroxy-[1,3]-oxathiolane-2-carboxylic acid menthy... (2R,5R)-5-Hydroxy[1,3]oxathiolane-2-carboxylic Acid L-Menthol Ester, Menthyloxathiolane (2R,5R)-5-Hydroxy-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)-cyclohexyl ester?(HME) (2R,5R)-5-Hydroxy-[1,3]-oxathiolane-2-carboxylic acid menthyl ester (HME) (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl (2R,5R)-5-hydroxy-1,3-oxathiolane-2-carboxylate (2R,5R)-5-Hydroxy-1.3 oxathiolane-2-carboxylie acid (1R,2S,5R)-5-methyl-2- (1-methylethyI)cyclohexyl ester (HME Lamivudine Impurity 40 (2R)-5-Hydroxy[1,3]oxathiolane-2-carboxylic Acid L- menthol Ester (2R,5R)-5-Hydroxy-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl este (1R,2S,5R)-Lamivudine Impurity 32 [(5R)-5-Methyl-2-propan-2-ylcyclohexyl](2R)-5-hydroxy-1,3-oxathiolane-2-carboxylate 147126-62-3 C14H24O4S Chiral Reagents Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds