ChemicalBook > Product Catalog >Organic Chemistry >Amides >4-Methylhistamine dihydrochloride

4-Methylhistamine dihydrochloride

CAS No.: 36376-47-3

Chemical Name:: 4-Methylhistamine dihydrochloride

Synonyms: SKF-71517;4-Methylhistamine di;4-Methylhistamine DiHCl;4-METHYLHISTAMINE DIHYDROCHLORIDE;5-Methylhistamine dihydrochloride;4-Methylhistamine (hydrochloride);Methylhistamine dihydrochloride, 4-;2-(4-methyl-1H-imidazol-5-yl)ethanamine;5-Methyl-1H-imidazole-4-ethanamine dihydrochloride;4-(2-Aminoethyl)-5-methylimidazole dihydrochloride

CBNumber:: CB9838358

Molecular Formula:: C6H14Cl2N3

Molecular Weight:: 199.10146

MOL File:: 36376-47-3.mol

Modify Date:: 2025/4/17 18:22:24

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4-Methylhistamine dihydrochloride Properties

Melting point	231-233℃ (ethanol )
storage temp.	Desiccate at RT
solubility	DMSO (Slightly, Heated), Methanol (Slightly)
form	Solid
color	White to Pale Beige
Water Solubility	Soluble to 50 mM in water

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H335-H315-H319

Precautionary statements

P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P

HazardClass

IRRITANT

NFPA 704

	0
2		0

4-Methylhistamine dihydrochloride Chemical Properties,Uses,Production

Description

4-Methylhistamine (dihydrochloride) is the potent agonist of histamine 4 receptor (H4R). 4-Methylhistamine (dihydrochloride) has the potential for the research of immune-related diseases such as cancer and autoimmune disorders.

Uses

Histamine H2 receptor agonist, antagonist and antineoplastic agent on the in vitro growth of peripheral blood CFU-GM from normal individuals and HL-60 leukemia cells.

Biological Activity

4-Methylhistamine dihydrochloride is a potent, high affinity H4 receptor agonist (Ki = 7 nM) that displays > 100-fold selectivity over other human histamine receptor subtypes.

4-Methylhistamine dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

4-Methylhistamine dihydrochloride Suppliers

Global( 53)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CHEMSWORTH	+91-261-2397244	New Delhi, India	6700	30	Inquiry
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	China	52849	58	Inquiry
Henan Alfa Chemical Co., Ltd	+8615838112936	China	13194	58	Inquiry
PT CHEM GROUP LIMITED	+86-85511178; +86-85511178;	China	35425	58	Inquiry
GIHI CHEMICALS CO.,LIMITED	+8618058761490	China	49984	58	Inquiry
Protheragen-ING	+16313385890	United States	3868	58	Inquiry
Aladdin Scientific		United States	52924	58	Inquiry
Amadis Chemical Company Limited	571-89925085	China	131957	58	Inquiry
Shanghai Haoyang Biological Technology Co., Ltd.	021-54046790 15121098156	CHINA	2905	58	Inquiry
Shanghai Yuda Industrial Co., Ltd.	021-64133189 13788995069	CHINA	6105	58	Inquiry

Supplier	Advantage
CHEMSWORTH	30
Dayang Chem (Hangzhou) Co.,Ltd.	58
Henan Alfa Chemical Co., Ltd	58
PT CHEM GROUP LIMITED	58
GIHI CHEMICALS CO.,LIMITED	58
Protheragen-ING	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58
Shanghai Haoyang Biological Technology Co., Ltd.	58
Shanghai Yuda Industrial Co., Ltd.	58

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5-(2-AMINOETHYL)-4-METHYLIMIDAZOLE DIHYDROCHLORIDE 4-METHYLHISTAMINE DIHYDROCHLORIDE SKF-71517 1H-Imidazole-4-ethanamine, 5-methyl-, dihydrochloride (9ci) 4-(2-Aminoethyl)-5-methylimidazole dihydrochloride 5-Methyl-1H-imidazole-4-ethanamine dihydrochloride 5-Methylhistamine dihydrochloride Imidazole, 4-(2-aminoethyl)-5-methyl-, dihydrochloride 2-(4-methyl-1H-imidazol-5-yl)ethanamine dihydrochloride 2-(5-Methyl-1H-iMidazol-4-yl)ethanaMine dihydrochloride 2-(5-Methyl-4-imidazolyl)ethylamine dihydrochloride 2-(4-methyl-1H-imidazol-5-yl)ethanamine 4-Methylhistamine (hydrochloride) 4-Methylhistamine DiHCl Methylhistamine dihydrochloride, 4- 4-Methylhistamine di 36376-47-3 Histamine receptor Amines Heterocycles Intermediates & Fine Chemicals Pharmaceuticals