ZK 200775

CAS No.: 161605-73-8

Chemical Name:: ZK 200775

Synonyms: MPQX;Fanapanel;ZK 200775;Fanapanel(ZK200775);MPQX;ZK200775;ZK-200775;7-Morpholino-2,3-dioxo-6-(trifluoromethyl)-1,2,3,4-tetrahydroquinoxalin-1-ylmethylphosphonic acid;[[3,4-Dihydro-7-(4-morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]phosphonicacid;[[3,4-DIHYDRO-7-(4-MORPHOLINYL)-2,3-DIOXO-6-(TRIFLUOROMETHYL)-1(2H)-QUINOXALINYL]METHYL]PHOSPHONIC ACID;P-[[3,4-Dihydro-7-(4-morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]phosphonic acid;Phosphonic acid, P-[[3,4-dihydro-7-(4-morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]-

CBNumber:: CB9848467

Molecular Formula:: C14H15F3N3O6P

Molecular Weight:: 409.25

MOL File:: 161605-73-8.mol

Modify Date:: 2023/6/30 15:45:59

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ZK 200775 Properties

Density	1.615±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,2-8°C
solubility	DMSO: ≥20mg/mL
pka	2.09±0.10(Predicted)
form	powder
color	off-white to light brown

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H319-H335-H302+H312+H332-H315
Precautionary statements	P280-P301+P312-P305+P351+P338
WGK Germany	3
HS Code	2934999090

ZK 200775 Chemical Properties,Uses,Production

Uses

ZK 200775 is a competitive AMPA/kainate antagonist. Neuronal protection against cerebral ischemia.

Biological Activity

Competitive AMPA/kainate antagonist. In rat cortical membranes, displays high affinity for [ 3 H]-AMPA (K i = 120 nM) and [ 3 H]-CNQX (K i = 32 nM) binding sites and low affinity for kainate and NMDA channel-associated binding sites (IC 50 values range from 2.5 to 11 μ M). Inhibits currents induced by AMPA, kainate and NMDA with IC 50 values of 21 nM, 27 nM, and > 1 μ M respectively. Displays anxiolytic, anticonvulsant and muscle relaxant activity in vivo .

ZK 200775 Preparation Products And Raw materials

Raw materials

Preparation Products

ZK 200775 Suppliers

Global( 54)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
Jilin Chinese Academy of Sciences-yanshen Technology	+undefined18143011203	China	42057	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	52927	58	Inquiry
Amadis Chemical Company Limited	571-89925085	China	131980	58	Inquiry
Beijing Bai Ao Si Biotechnology Co., Ltd.	010-60291560	CHINA	6999	58	Inquiry
Qingdao Jieshikang Biotechnology Co., Ltd.	4009025885 18754289606	CHINA	4012	58	Inquiry
Shanghai Haoyang Biological Technology Co., Ltd.	021-54046790 15121098156	CHINA	2905	58	Inquiry
Guangzhou Weijia Technology Co., Ltd.	020-84224925 18300190102	CHINA	6748	58	Inquiry
Xiamen Huijia Biological Technology Co., Ltd.	0592-6020891	CHINA	6979	58	Inquiry
Xiamen Research Biotechnology Co., Ltd.	0592-6020891 18906011628	CHINA	6942	58	Inquiry

Supplier	Advantage
TargetMol Chemicals Inc.	58
Jilin Chinese Academy of Sciences-yanshen Technology	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58
Beijing Bai Ao Si Biotechnology Co., Ltd.	58
Qingdao Jieshikang Biotechnology Co., Ltd.	58
Shanghai Haoyang Biological Technology Co., Ltd.	58
Guangzhou Weijia Technology Co., Ltd.	58
Xiamen Huijia Biological Technology Co., Ltd.	58
Xiamen Research Biotechnology Co., Ltd.	58

161605-73-8(ZK 200775)Related Search:

2,3-Quinoxalinedione,6-amino-1,4-dihydro-(9CI) 1,2,3,4-Tetrahydro-quinoxalin-6-ylamine ZK 200775 2-Amino-5-acetamidobenzotrifluoride

ZK 200775 [[3,4-Dihydro-7-(4-morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]phosphonicacid Fanapanel MPQX 7-Morpholino-2,3-dioxo-6-(trifluoromethyl)-1,2,3,4-tetrahydroquinoxalin-1-ylmethylphosphonic acid [[3,4-Dihydro-7-(4-morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]-phosphonic acid hydrate P-[[3,4-Dihydro-7-(4-morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]phosphonic acid [[3,4-DIHYDRO-7-(4-MORPHOLINYL)-2,3-DIOXO-6-(TRIFLUOROMETHYL)-1(2H)-QUINOXALINYL]METHYL]PHOSPHONIC ACID Phosphonic acid, P-[[3,4-dihydro-7-(4-morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]- MPQX;ZK200775;ZK-200775 Fanapanel(ZK200775) 161605-73-8 C14H15F3N3O6P C14H15N3O6F3P