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Disitertide

化学構造式
272105-42-7
CAS番号.
272105-42-7
化学名:
别名:
英語名:
Disitertide
英語别名:
disitertide;P144 Peptide;TSLDASIIWAMMQN;P144;P144 PEPTIDE;DISITERTIDE, >98%;Disitertide,P144,P144 Peptide, >98%;DisitertideH-Gly-Arg-Gly-Asp-Asn-Pro-OH;L-Asparagine,L-threonyl-L-seryl-L-leucyl-L-a-aspartyl-L-alanyl-L-seryl-L-isoleucyl-L-isoleucyl-L-tryptophyl-L-alanyl-L-methionyl-L-methionyl-L-glutaminyl-;L-Asparagine, L-threonyl-L-seryl-L-leucyl-L-α-aspartyl-L-alanyl-L-seryl-L-isoleucyl-L-isoleucyl-L-tryptophyl-L-alanyl-L-methionyl-L-methionyl-L-glutaminyl-;L-Threonyl-L-seryl-L-leucyl-L-alpha-aspartyl-L-alanyl-L-seryl-L-isoleucyl-L-isoleucyl-L-tryptophyl-L-alanyl-L-methionyl-L-methionyl-L-glutaminyl-L-asparagine
CBNumber:
CB01518504
化学式:
C68H109N17O22S2
分子量:
1580.84
MOL File:
272105-42-7.mol

Disitertide 物理性質

沸点 :
1968.7±65.0 °C(Predicted)
比重(密度) :
1.327
貯蔵温度 :
Store at -20°C
溶解性:
DMSO : ≥ 200 mg/mL (126.52 mM);Water : < 0.1 mg/mL (insoluble)
酸解離定数(Pka):
3.15±0.10(Predicted)
外見 :
Solid
色:
White to off-white
InChIKey:
IUYPEUHIWDMJLM-INGCBPSVNA-N

安全性情報

Disitertide 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

Disitertide 化学特性,用途語,生産方法

説明

Disitertide is an inhibitor of TGF-β1. It prevents TGF-β1-dependent inhibition of MV1Lu proliferation in vitro and markedly reduces binding of TGF-β1 to its receptors. Disitertide blocks TGF-β1-dependent stimulation of a reporter gene under the control of human α2(I) collagen promoter. Treatment with Disitertide at low doses causes a significant inhibition of HSC activation and a marked reduction in liver fibrosis in a rat model of chronic exposure to CCl4. A dose as low as 70 μg of the 15-mer peptide Disitertide, given to rats (300 g body weight) on alternate days, decreases fibrogenesis significantly during chronic exposure to CCl4.

Disitertide 上流と下流の製品情報

原材料

準備製品

Disitertide 生産企業

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272105-42-7()キーワード:

L-アラニル-L-グルタミン ジエチルスチルベストロール Γ-グルタミルトランスフェラーゼ L-アスパラギン FMOC-ASN(TRT)-OPFP L-グルタミン
  • 272105-42-7
  • disitertide
  • L-Threonyl-L-seryl-L-leucyl-L-alpha-aspartyl-L-alanyl-L-seryl-L-isoleucyl-L-isoleucyl-L-tryptophyl-L-alanyl-L-methionyl-L-methionyl-L-glutaminyl-L-asparagine
  • P144 Peptide
  • P144;P144 PEPTIDE
  • TSLDASIIWAMMQN
  • DISITERTIDE, >98%
  • Disitertide,P144,P144 Peptide, >98%
  • L-Asparagine, L-threonyl-L-seryl-L-leucyl-L-α-aspartyl-L-alanyl-L-seryl-L-isoleucyl-L-isoleucyl-L-tryptophyl-L-alanyl-L-methionyl-L-methionyl-L-glutaminyl-
  • DisitertideH-Gly-Arg-Gly-Asp-Asn-Pro-OH
  • L-Asparagine,L-threonyl-L-seryl-L-leucyl-L-a-aspartyl-L-alanyl-L-seryl-L-isoleucyl-L-isoleucyl-L-tryptophyl-L-alanyl-L-methionyl-L-methionyl-L-glutaminyl-
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