プロトリプチリン

プロトリプチリン 化学構造式
438-60-8
CAS番号.
438-60-8
化学名:
プロトリプチリン
别名:
N-メチル-5H-ジベンゾ[a,d]シクロヘプテン-5-(1-プロパンアミン);トリプチル;N-メチル-3-(5H-ジベンゾ[a,d]シクロヘプテン-5-イル)-1-プロパンアミン;N-メチル-5H-ジベンゾ[a,d]シクロヘプテン-5-プロパン-1-アミン;プロトリプチリン;メチル(3-{トリシクロ[9.4.0.03,8]ペンタデカ-1(15),3,5,7,9,11,13-ヘプタエン-2-イル}プロピル)アミン
英語名:
PROTRIPTYLINE
英語别名:
Triptil;Vivactil;Amimetilina;Protriptylin;PROTRIPTYLINE;Protryptyline;Protriptyline-d6;Protriptyline 13CD3;DIBENZO(A,D)CYCLOHEPTENE-5-PROPYLAMINE,N-METHYL-;3-(dibenzo(a,d)cyclohepten-5-yl)propylmethylamine
CBNumber:
CB0774981
化学式:
C19H21N
分子量:
263.38
MOL File:
438-60-8.mol

プロトリプチリン 物理性質

沸点 :
396.62°C (rough estimate)
比重(密度) :
0.9076 (rough estimate)
屈折率 :
1.7500 (estimate)
酸解離定数(Pka):
8.2(at 25℃)
EPAの化学物質情報:
Protriptyline (438-60-8)

安全性情報

有毒物質データの 438-60-8(Hazardous Substances Data)

プロトリプチリン 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

プロトリプチリン 化学特性,用途語,生産方法

効能

抗うつ薬

使用

Protriptyline is a powerful antidepressant, the mechanism of action of which is not known. It is not a MAO inhibitor and does not stimulate the CNS. It begins to act much faster and acts much longer than imipramine or amitriptyline. Protriptyline does not possess sedative tranquilizing properties. It is used in clinical conditions for treating severe depression.

作用機序

Protriptyline exhibits high selectivity for the NE transporter, but with less potency than desipramine. Its mechanism of action is similar to that of desipramine. Minimal effect on 5-HT reuptake has been observed.

代謝

Protriptyline is a dibenzocycloheptriene TCA that differs from the other tricyclics by having an unsaturated ethylene bridge joining the two aromatic rings and a secondary aminopropyl side chain. Protriptyline is completely absorbed from the GI tract and slowly eliminated. Metabolism data are limited for protriptyline, but it is most likely to be metabolized via the same pathways as the other TCAs are. Very little drug is excreted in the feces via the bile.

プロトリプチリン 上流と下流の製品情報

原材料

準備製品


プロトリプチリン 生産企業

Global( 29)Suppliers
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Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
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Hubei Jusheng Technology Co.,Ltd.
18871490254
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Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684
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Shaanxi DIDU pharmaceutical and Chemical Co., Ltd 17691182729 18161915376
1046@dideu.com China 10011 58
TargetMol Chemicals Inc. 4008200310
marketing@tsbiochem.com China 24017 58
Nanjing Shizhou Biology Technology Co.,Ltd 17301488900
judy.xia@synzest.com China 12584 58

438-60-8(プロトリプチリン)キーワード:


  • 438-60-8
  • PROTRIPTYLINEHYDROCHLORIDE,1.0MG/ML(FREEBASE)INMETHANOL
  • DIBENZO(A,D)CYCLOHEPTENE-5-PROPYLAMINE,N-METHYL-
  • N-Methyl-5H-dibenzo[a,d]cycloheptene-5-propan-1-amine
  • Protriptyline-d6
  • PROTRIPTYLINE
  • 3-(5H-Dibenzo[a,d]cyclohepten-5-yl)-N-methyl-1-propanamine
  • 5-(3-Methylaminopropyl)-5H-Dibenzo[a,d]cycloheptene
  • 5H-Dibenzo[a,d]cycloheptene-5-propanamine, N-methyl-
  • 5H-Dibenzo[a,d]cycloheptene-5-propylamine, N-methyl-
  • 7-(3-Methylaminopropyl)-1,2:5,6-dibenzocycloheptatriene
  • Amimetilina
  • N-3-(5H-Dibenzo(a,d)cyclohepten-5-yl)propyl-N-methylamine
  • N-Methyl-5H-dibenzo[a,d]cycloheptene-5-propylamine
  • Protryptyline
  • Triptil
  • Vivactil
  • 3-(dibenzo(a,d)cyclohepten-5-yl)propylmethylamine
  • 3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-1-amine
  • Protriptylin
  • Protriptyline 13CD3
  • N-メチル-5H-ジベンゾ[a,d]シクロヘプテン-5-(1-プロパンアミン)
  • トリプチル
  • N-メチル-3-(5H-ジベンゾ[a,d]シクロヘプテン-5-イル)-1-プロパンアミン
  • N-メチル-5H-ジベンゾ[a,d]シクロヘプテン-5-プロパン-1-アミン
  • プロトリプチリン
  • メチル(3-{トリシクロ[9.4.0.03,8]ペンタデカ-1(15),3,5,7,9,11,13-ヘプタエン-2-イル}プロピル)アミン
  • 三環式抗欝薬
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