トルセミド
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBQA-4191 |
トラセミド
Torasemide |
56211-40-6 |
1g |
￥10000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBQA-4191 |
トラセミド
Torasemide |
56211-40-6 |
5g |
￥12500 |
2024-03-01 |
購入 |
|
東京化成工業
|
T2538 |
トルセミド >98.0%(HPLC)(T)
Torsemide
>98.0%(HPLC)(T) |
56211-40-6 |
1g |
￥12800 |
2024-03-01 |
購入 |
|
東京化成工業
|
T2538 |
トルセミド >98.0%(HPLC)(T)
Torsemide
>98.0%(HPLC)(T) |
56211-40-6 |
5g |
￥37600 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
T3202 |
トルセミド ≥98% (HPLC), solid
Torsemide ≥98% (HPLC), solid |
56211-40-6 |
10mg |
￥24100 |
2024-03-01 |
購入 |
トルセミド 化学特性,用途語,生産方法
外観
白色～ほとんど白色粉末～結晶
効能
利尿薬, Na-K-Cl共輸送体阻害薬
商品名
ルプラック (田辺三菱製薬)
説明
Torasemide is a novel loop diuretic launched in 1993 after a 12-year gap from the last
diuretic introduction. It is indicated for the treatment of hypertension and edema associated
with chronic congestive heart failure, renal disease and hepatic cirrhosis. Torasemide exerts
its major diuretic activity on the thick ascending limb of the Henle's loop to promote rapid and
marked excretion of water, Na
+, Cl
-, and to a lesser extent,K
+ and Ca
2+. Compared with other
loop diuretics such as furosemide, torasemide has a stronger antihypertensive action, a
higher bioavailability, a longer duration of action that is independent of the renal function, and
has no side effects such as paradoxical antidiuresis. The mechanism of its vasodilating effect
has been suggested to result from, at least in part, the competitive antagonism of the
thromboxane A2 receptor.
化学的特性
Crystalline Solid
使用
Torasemide is a loop diuretic. Diuretics have been abused as performance-enhancing drugs and masking agents in doping in sports. Use of torsemide is effective for the treatment of edema associated with chronic renal failure. The pharmacology of torasemide is similar to that of frusemide,though torasemide has a longer duration of action with a plasma half-life of approximately 3.5 hours. It also causes a less marked loss of potassiumand calcium.
定義
ChEBI: Torasemide is an N-sulfonylurea obtained by formal condensation of [(3-methylphenyl)amino]pyridine-3-sulfonic acid with the free amino group of N-isopropylurea. It is a potent loop diuretic used for the treatment of hypertension and edema in patients with congestive heart failure. It has a role as a loop diuretic and an antihypertensive agent. It is a N-sulfonylurea, an aminopyridine and a secondary amino compound. It is functionally related to a 4-aminopyridine.
トルセミド 上流と下流の製品情報
原材料
準備製品
トルセミド 生産企業
Global( 412)Suppliers
56211-40-6(トルセミド)キーワード:
- 56211-40-6
- TorseMide(DeMadex)
- TorseMide API
- N-(Isopropylcarbamoyl)-4-(m-tolylamino)pyridine-3-sulfonamide
Torasemide
- TroseMide
- Torasemide Tables
- N-[(isopropylamino)carbonyl]-4-[(3-methylphenyl)amino]pyridine-3-sulfonamide
- JDL-464
- BM-02015
- 3-pyridinesulfonamide,n-(((1-methylethyl)amino)carbonyl)-4-((3-methylphenyl)am
- AC-4464
- 1-[4-(3-methylphenyl)aminopyridin-3-yl]sulfonyl-3-propan-2-yl-urea
- LUPLAC
- N-[[(1-METHYLETHYL)AMINO]CARBONYL]-4-[(3-METHYLPHENYL)AMINO]-3-PYRIDINESULFONAMIDE
- TORADIUR
- TOREM
- TORASEMIDE
- N-[4-(3-methylphenyl)aminopyridin-3-yl]sulfonylmethanamide
- N-[[(1-Methylethyl)amino]carbonyl]-4-[(3-methylphenyl)amino]-3-pyridinesulfonamide, AC-4464, BM-02015, JDL-464, Demadex, Luplac, Toradiur, Torem, Torasemide.
- TORASEMIDE(SUBJECTTOPATENTFREE)
- 3-Pyridinsulfonamid, N-(((1-methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-
- n-(((1-methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfo
- TORASEMIDE,TORSEMIDE
- TorsemideUsp2598-102%
- N-(Isopropylcarbamoyl)-4-(m-tolylamino)pyridine-3-sulfonamide
- 3-Pyridinesulfonamide, N-(((1-methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-
- Luprac
- GJ-1090
- N-(Isopropylaminocarbonyl)-4-[(3-methylphenyl)amino]-3-pyridinesulfonamide
- 1-[4-(3-methylanilino)pyridin-3-yl]sulfonyl-3-propan-2-ylurea
- 1-isopropyl-3-[[4-(3-methylanilino)-3-pyridyl]sulfonyl]urea
- トルセミド
- ルプラック
- トラセミド
- N-(イソプロピルアミノカルボニル)-4-[(3-メチルフェニル)アミノ]-3-ピリジンスルホンアミド
- N-(イソプロピルカルバモイル)-4-(m-トリルアミノ)ピリジン-3-スルホンアミド
- トラセミド (JAN)
- 1-({4-[(3-メチルフェニル)アミノ]ピリジン-3-イル}スルホニル)-3-(プロパン-2-イル)尿素
- N-(イソプロピルアミノカルボニル)-4-(3-メチルフェニルアミノ)ピリジン-3-スルホンアミド
- 1-(4-(3-メチルアニリノ)-3-ピリジルスルホニル)-3-イソプロピル尿素
- N-(イソプロピルアミノカルボニル)-4-(3-メチルフェニルアミノ)ピリジン-3-イルスルホンアミド
- 生化学
- 薬理研究用試薬
- 医薬農薬成分(その他)
- 利尿薬