CALPAIN INHIBITOR XII 化学特性,用途語,生産方法
説明
Calpain inhibitor XII is a reversible and selective inhibitor of calpain I (μ-
calpain, K
i = 19 nM), with lower affinities for calpain II (m-
calpain, K
i = 120 nM) and cathepsin B (K
i = 750 nM). Calpain inhibitors, including this compound, have been used to study the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury.
使用
A cell-permeable dipeptidyl -ketoamide compound that acts as a potent, selective, reversible, and active site inhibitor of calpain-1
CALPAIN INHIBITOR XII 上流と下流の製品情報
原材料
準備製品