칼페인억제제XII

칼페인억제제XII
칼페인억제제XII 구조식 이미지
카스 번호:
181769-57-3
한글명:
칼페인억제제XII
동의어(한글):
칼페인억제제XII
상품명:
CALPAIN INHIBITOR XII
동의어(영문):
CALPAIN INHIBITOR XII;Z-L-NVA-CONH-CH2-2-PY;PLVWMBFPIAQRHK-UHFFFAOYSA-N;(Rac)-Calpain Inhibitor XII;benzyl N-[1-[[1,2-dioxo-1-(pyridin-2-ylmethylamino)hexan-3-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate;Carbamic acid, [3-methyl-1-[[[1-[oxo[(2-pyridinylmethyl)amino]acetyl]butyl]amino]carbonyl]butyl]-, phenylmethyl ester (9CI)
CBNumber:
CB2243292
분자식:
C26H34N4O5
포뮬러 무게:
482.57
MOL 파일:
Mol file

칼페인억제제XII 속성

밀도
1.167±0.06 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
≤16mg/ml in ethanol;16mg/ml in DMSO;20mg/ml in dimethyl formamide
물리적 상태
결정질 고체
산도 계수 (pKa)
10.58±0.46(Predicted)
색상
White to yellow

안전

칼페인억제제XII C화학적 특성, 용도, 생산

개요

Calpain inhibitor XII is a reversible and selective inhibitor of calpain I (μ-calpain, Ki = 19 nM), with lower affinities for calpain II (m-calpain, Ki = 120 nM) and cathepsin B (Ki = 750 nM). Calpain inhibitors, including this compound, have been used to study the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury.

용도

A cell-permeable dipeptidyl -ketoamide compound that acts as a potent, selective, reversible, and active site inhibitor of calpain-1

칼페인억제제XII 준비 용품 및 원자재

원자재

준비 용품


칼페인억제제XII 공급 업체

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VDM Biochemicals 0330-2528181
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BOC Sciences 16314854226
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Hangzhou Peptidego Biotech Co.,Ltd. 0571-87213919
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Angel Pharmatech, Ltd. 17317130613
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ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
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MedBioPharmaceutical Technology Inc 021-69568360 18916172912
order@med-bio.cn China 8141 58
Wuhan Topule +86-02787215551 +86-19945035818
2936752263@qq.com China 8193 58

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