CALPAIN INHIBITOR XII

CALPAIN INHIBITOR XII Struktur
181769-57-3
CAS-Nr.
181769-57-3
Englisch Name:
CALPAIN INHIBITOR XII
Synonyma:
CALPAIN INHIBITOR XII;Z-L-NVA-CONH-CH2-2-PY;PLVWMBFPIAQRHK-UHFFFAOYSA-N;(Rac)-Calpain Inhibitor XII;benzyl N-[1-[[1,2-dioxo-1-(pyridin-2-ylmethylamino)hexan-3-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate;Carbamic acid, [3-methyl-1-[[[1-[oxo[(2-pyridinylmethyl)amino]acetyl]butyl]amino]carbonyl]butyl]-, phenylmethyl ester (9CI)
CBNumber:
CB2243292
Summenformel:
C26H34N4O5
Molgewicht:
482.57
MOL-Datei:
Mol file

CALPAIN INHIBITOR XII Eigenschaften

Dichte
1.167±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
Löslichkeit
≤16mg/ml in ethanol;16mg/ml in DMSO;20mg/ml in dimethyl formamide
Aggregatzustand
crystalline solid
pka
10.58±0.46(Predicted)
Farbe
White to yellow

Sicherheit

CALPAIN INHIBITOR XII Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Calpain inhibitor XII is a reversible and selective inhibitor of calpain I (μ-calpain, Ki = 19 nM), with lower affinities for calpain II (m-calpain, Ki = 120 nM) and cathepsin B (Ki = 750 nM). Calpain inhibitors, including this compound, have been used to study the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury.

Verwenden

A cell-permeable dipeptidyl -ketoamide compound that acts as a potent, selective, reversible, and active site inhibitor of calpain-1

CALPAIN INHIBITOR XII Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


CALPAIN INHIBITOR XII Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 39)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Nantong HI-FUTURE Biology Co., Ltd.
+undefined18051384581
sales@chemhifuture.com China 3136 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525
masar@topule.com China 8474 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 52927 58
VDM Biochemicals 0330-2528181
sales@vdmbio.com United States 510 64
BOC Sciences 16314854226
info@bocsci.com United States 9926 65
Hangzhou Peptidego Biotech Co.,Ltd. 0571-87213919
eric@peptidego.com China 6526 58
Angel Pharmatech, Ltd. 17317130613
3358272972@qq.com China 3246 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
sales@chemegen.com China 11289 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912
order@med-bio.cn China 8141 58
Wuhan Topule +86-02787215551 +86-19945035818
2936752263@qq.com China 8234 58

  • Z-L-NVA-CONH-CH2-2-PY
  • CALPAIN INHIBITOR XII
  • (Rac)-Calpain Inhibitor XII
  • Carbamic acid, [3-methyl-1-[[[1-[oxo[(2-pyridinylmethyl)amino]acetyl]butyl]amino]carbonyl]butyl]-, phenylmethyl ester (9CI)
  • PLVWMBFPIAQRHK-UHFFFAOYSA-N
  • benzyl N-[1-[[1,2-dioxo-1-(pyridin-2-ylmethylamino)hexan-3-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate
  • 181769-57-3
  • C26H34N4O5
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