酢酸セルモレリン 化学特性,用途語,生産方法
効能
診断薬 (下垂体機能判定), 成長ホルモン放出ホルモン受容体作動薬
説明
Sermorelin acetate, also known as INN/Geref/Gerel, is a peptide analogue of growth hormone-releasing hormone (GHRH) used as a diagnostic agent to evaluate growth hormone (GH) secretion and diagnose growth hormone deficiency. It is a 29 amino acid polypeptide representing fragments 1-29 from endogenous human GHRH and is considered to be the shortest fully functional fragment of GHRH.
利点
The benefits of using Sermorelin acetate therapy are multifaceted and include: helping to increase muscle strength, weight loss, improved bone mineral density, improved cognitive health, increased energy levels, restoration of sexual dysfunction, improvement of cardiovascular disease, enhancement of the immune system, improvement of skin health, and a boost in metabolism.
副作用
All medicines may cause side effects, but many have no or minor side effects. The most common side effects:
Facial flushing; headache; nausea; pain, redness, or swelling at the injection site; paleness; strange taste in mouth; vomiting.
The Severe side effects :
Severe allergic reactions (rash, hives, itching, difficulty breathing, tightness in the chest, swelling of the mouth, face, lips, or tongue).
参考文献
Influence of growth hormone (GH) and GH-releasing factor on locomotor activity in rats DOI:
10.1016/0196-9781(93)90101-LComparison of GH-stimulation by GH-RH(1-29)NH2 and an agmatine29 GH-RH analog, after intravenous, subcutaneous and intranasal administration and after pulmonary inhalation in rats DOI:
10.1111/j.1399-3011.1993.tb00332.x Potent agonists of growth hormone-releasing hormone Part I DOI:
10.1111/j.1399-3011.1992.tb00791.xSynthesis and in vitro and in vivo activity of analogs of growth hormone-releasing hormone (GH-RH) with C-terminal agmatine DOI:
10.1111/j.1399-3011.1990.tb00988.xGrowth-hormone-releasing hormone DOI:
10.1093/clinchem/36.3.415
酢酸セルモレリン 上流と下流の製品情報
原材料
準備製品