N-[(S)-6-オキソ-2-ピペリジニルカルボニル]-L-Leu-L-Pro-NH2 化学特性,用途語,生産方法
説明
Posatirelin is a TRH analogue. In a rat experimental model of brain cholinergic decit by lesion of the nucleus basalis magnocellularis (nbM), posatirelin treatment rescued cholinergic neurones of the nbM and their cholinergic projections to the cerebral cortex (Sabbatini et al., 1998). Posatirelin has been used in AD and VaD patients (Parnetti et al., 1995, 1996). VaD patients treated with posatirelin showed a signicant improvement in intellectual performance, orientation, motivation and memory as compared to controls. e drug was well tolerated.
使用
Posatirelin is a thyrotropin-releasing hormone analogue, used in the treatment of seizures and some neurodegenerative disease such as vascular dementia and Parkinson''s disease.
N-[(S)-6-オキソ-2-ピペリジニルカルボニル]-L-Leu-L-Pro-NH2 上流と下流の製品情報
原材料
準備製品