포사티렐린

포사티렐린
포사티렐린 구조식 이미지
카스 번호:
78664-73-0
한글명:
포사티렐린
동의어(한글):
포사티렐린
상품명:
Posatirelin
동의어(영문):
RGH-2202;BRN6006446;BRN 6006446;BRN-6006446;Posatirelin;Posatirelinum;N-[(S)-6-Oxo-2-piperidinylcarbonyl]-L-Leu-L-Pro-NH2;L-Prolinamide, (2S)-6-oxo-2-piperidinecarbonyl-L-leucyl-;N-[6-Oxopiperidin-2(S)-Ylcarbonyl]-L-Leucyl-L- Prolinamide
CBNumber:
CB51179553
분자식:
C17H28N4O4
포뮬러 무게:
352.432
MOL 파일:
78664-73-0.mol

포사티렐린 속성

녹는점
214-216°
알파
D25 -80.2° (c = 1 in acetic acid)
끓는 점
739.6±60.0 °C(Predicted)
밀도
1.214±0.06 g/cm3(Predicted)
산도 계수 (pKa)
13.56±0.20(Predicted)

안전

포사티렐린 C화학적 특성, 용도, 생산

개요

Posatirelin is a TRH analogue. In a rat experimental model of brain cholinergic decit by lesion of the nucleus basalis magnocellularis (nbM), posatirelin treatment rescued cholinergic neurones of the nbM and their cholinergic projections to the cerebral cortex (Sabbatini et al., 1998). Posatirelin has been used in AD and VaD patients (Parnetti et al., 1995, 1996). VaD patients treated with posatirelin showed a signicant improvement in intellectual performance, orientation, motivation and memory as compared to controls. e drug was well tolerated.

용도

Posatirelin is a thyrotropin-releasing hormone analogue, used in the treatment of seizures and some neurodegenerative disease such as vascular dementia and Parkinson''s disease.

포사티렐린 준비 용품 및 원자재

원자재

준비 용품


포사티렐린 공급 업체

글로벌( 6)공급 업체
공급자 전화 이메일 국가 제품 수 이점
TargetMol Chemicals Inc.
+1-781-999-5354
support@targetmol.com United States 19973 58
Jiangsu Hongmin Pharmaceutical Co., Ltd. 18221292452
fannieliu@glschina.com China 6799 58
TargetMol Chemicals Inc. 4008200310
marketing@tsbiochem.com China 24016 58

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