アルゾキシフェン 化学特性,用途語,生産方法
臨床応用
Arzoxifene is a third-generation SERM currently in Phase III clinical trials for the treatm ent of ER-positive recurrent/metastatic breast cancer. Similar to raloxifene, it is an ER antagonist in both breast and uterine tissues and an ER agonist on bone and the cardiovascular system. Arzoxifene is able to both preserve and build bone mineral density, which makes it a viable candidate for the treatment of osteoporosis. Ample evidence from early clinical trials indicates that arzoxifene also can be utilized as a chemopreventive agent against breast cancer.
副作用
Adverse effects include hot flashes (major) and headache, nausea, vomiting, and constipation (minor).
アルゾキシフェン 上流と下流の製品情報
原材料
準備製品