MIP-1Α ヒト

MIP-1Α ヒト 価格

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入

MIP-1Α ヒト 化学特性,用途語,生産方法

一般的な説明

MIP-1α (microphage inflammatory protein-1α), or CCL3 (C-C motif chemokine ligand 3), was originally isolated from the supernatant of endotoxin-stimulated murine macrophages. It is an 8kDa chemokine; chemokines are a type of chemotactic cytokines.

Biochem/physiol Actions

MIP-1α (microphage inflammatory protein-1α), or CCL3 (C-C motif chemokine ligand 3), and its receptors- CCR1 and CCR5- promote tumor growth and control osteoclast differentiation, thereby contributing to bone disease progression in multiple myeloma. It suppresses the expression of miR-374b through JNK (Janus kinase), ERK (extracellular signal-regulated kinases), and p38 pathways, thus, facilitating VEGF-A (vascular endothelial growth factor) expression and angiogenesis in human osteosarcoma cells. In chondrosarcoma cells, this protein promotes the up-regulation of matrix metalloproteinase-2 (MMP)-2, thus, promoting cell migration and metastasis.

MIP-1Α ヒト 上流と下流の製品情報

原材料

準備製品

MIP-1Α ヒト 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15421	60
United States Biological	--	sales@advtechind.com	United States	6106	58

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• REC MIP-1A (HUMAN)
• REC MIP-1ALPHA (HUMAN)
• REC MACROPHAGE INFLAMMATORY PROTEIN-1A (HUMAN)
• REC MACROPHAGE INFLAMMATORY PROTEIN-1ALPHA (HUMAN)
• RHMIP-1ALPHA
• MIP1A [HOMO SAPIENS]
• MIP-1A, HUMAN
• MIP-1ALPHA
• MIP-1ALPHA, HUMAN
• MACROPHAGE INFLAMMATORY PROTEIN-1 ALPHA
• MACROPHAGE INFLAMMATORY PROTEIN-1ALPHA, HUMAN
• MACROPHAGE INFLAMMATORY PROTEIN-1ALPHA, HUMAN, RECOMBINANT
• MACROPHAGE INFLAMMATORY PROTEIN-1ALPHA, HUMAN, RECOMBINANT, E COLI
• MACROPHAGE INFLAMMATORY PROTEIN, ALPHA-1, HUMAN
• HUMAN RECOMBINANT MIP-1 ALPHA
• HUMAN CCL3
• HUMAN MACROPHAGE INFLAMMATORY PROTEIN-1 ALPHA
• HUMAN MIP-1ALPHA
• HUMAN LD78 ALPHA
• Heparin-binding chemotaxis protein, L2G25B)
• MIP-1alpha, Recombinant, Mouse (Small inducible cytokine A3, CCL3, Macrophage inflammatory protein 1-&alpha
• PAT 464,1, chemokine (C-C motif) ligand 3, MIP1A, SCYA3, G0S19-1, LD78&alpha
• protein, G0/G1 switch regulatory protein 19-1, G0S19-1 protein, SIS-&beta
• Tonsillar lymphocyte LD78 &alpha
• TY-5, SIS-&alpha
• MIP-1Α ヒト