GANT61
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- CAS番号.
- 500579-04-4
- 化学名:
- GANT61
- 别名:
- GANT61;2,2′-[[5,6-ジヒドロ-2-(4-ピリジニル)-1,3(2H,4H)-ピリミジンジイル]ビスメチレン]ビス(N,N-ジメチルアニリン);2-[(3-{[2-(ジメチルアミノ)フェニル]メチル}-2-(ピリジン-4-イル)-1,3-ジアジナン-1-イル)メチル]-N,N-ジメチルアニリン;GANT-61;2-(4-ピリジニル)-1,3-ビス[2-(ジメチルアミノ)ベンジル]ヘキサヒドロピリミジン
- 英語名:
- 2,2'-[[Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethylbenzenamine
- 英語别名:
- GNT61;CS-867;GANT 61;NSC 136476;GANT61, >=98%;GANT-61,NSC 136476;GANT61;GANT 61;NSC 136476;GANT61; GANT-61; NSC 136476;GANT 61;InSolution? Hh/Gli Antagonist, GANT61;InSolution Hh/Gli Antagonist, GANT61 - CAS 500579-04-4 - Calbiochem
- CBNumber:
- CB72518922
- 化学式:
- C27H35N5
- 分子量:
- 429.6
- MOL File:
- 500579-04-4.mol
- MSDS File:
- SDS
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GANT61 物理性質
- 融点 :
- 110 - 113°C
- 沸点 :
- 549.0±50.0 °C(Predicted)
- 比重(密度) :
- 1.134±0.06 g/cm3(Predicted)
- 貯蔵温度 :
- 2-8°C
- 溶解性:
- DMSO:>2mg/mL
- 酸解離定数(Pka):
- 5.97±0.10(Predicted)
- 外見 :
- 粉
- 色:
- ホワイトからオフホワイト
メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
富士フイルム和光純薬株式会社(wako)
|
W01TOC3191 |
GANT61
GANT 61 |
500579-04-4 |
10mg |
¥64000 |
2024-03-01 |
購入 |
富士フイルム和光純薬株式会社(wako)
|
W01BVI1892-5 |
GANT61 |
500579-04-4 |
5mg |
¥42900 |
2020-09-21 |
購入 |
Sigma-Aldrich Japan
|
G9048 |
≥98% (HPLC)
GANT61 ≥98% (HPLC) |
500579-04-4 |
5mg |
¥35800 |
2024-03-01 |
購入 |
Sigma-Aldrich Japan
|
G9048 |
≥98% (HPLC)
GANT61 ≥98% (HPLC) |
500579-04-4 |
25mg |
¥109000 |
2024-03-01 |
購入 |
富士フイルム和光純薬株式会社(wako)
|
W01TOC3191 |
GANT61
GANT 61 |
500579-04-4 |
50mg |
¥272000 |
2024-03-01 |
購入 |
GANT61 化学特性,用途語,生産方法
使用
GANT61 is an inhibitor for GLI1 as well as GLI2-induced transcription, inhibits hedgehog, displays selectivity over other pathways, such as TNF and glucocorticoid receptor gene transactivation.
Biochem/physiol Actions
GANT61 blocks hedgehog pathway signaling by inhibiting the transcripional activity of Gli1 (IC50 = 5 μM). GANT 61 led to a regression of 22Rv1 human prostate tumor cell xenografts in nude mice.
GANT61 上流と下流の製品情報
原材料
準備製品
GANT61 生産企業
Global( 135)Suppliers
500579-04-4(GANT61)キーワード:
- 500579-04-4
- 2,2'-[[Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethylbenzenamine
- GANT 61
- Benzenamine, 2,2'-[[dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethyl-
- 2,2'-[[Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethylbenzenamine] GANT61
- GNT61
- NSC 136476
- GANT61, >=98%
- GANT-61,NSC 136476
- 2,2'-((2-(Pyridin-4-yl)dihydropyrimidine-1,3(2H,4H)-diyl)bis(methylene))bis(N,N-dimethylanilin
- InSolution? Hh/Gli Antagonist, GANT61
- 2-[[3-[[2-(dimethylamino)phenyl]methyl]-2-pyridin-4-yl-1,3-diazinan-1-yl]methyl]-N,N-dimethylaniline
- InSolution Hh/Gli Antagonist, GANT61 - CAS 500579-04-4 - Calbiochem
- CS-867
- GANT61; GANT-61; NSC 136476;GANT 61
- GANT61;GANT 61;NSC 136476
- 2,2'-[[Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethylbenzenamine USP/EP/BP
- 2,2'-((2-(Pyridin-4-yl)dihydropyrimidine-1,3(2H,4H)-diyl)bis(methylene))bis(N,N-dimethylaniline)
- 2,2’-[[2-(4-Pyridyl)dihydropyrimidine-1,3(2H,4H)-diyl]bis(methylene)]bis(N,N-dimethylaniline)
- 2,2'-[[Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethylbenzenamine
- 2,2’-[[2-(4-Pyridyl)dihydropyrimidine-1,3(2H,4H)-diyl]bis(methylene)]bis(N,N-dimethylaniline)
- 2,2'-((2-(Pyridin-4-yl)dihydropyrimidine-1,3(2H,4H)-diyl)bis(methylene))bis(N,N-dimethylaniline)
- GANT61
- 2,2′-[[5,6-ジヒドロ-2-(4-ピリジニル)-1,3(2H,4H)-ピリミジンジイル]ビスメチレン]ビス(N,N-ジメチルアニリン)
- 2-[(3-{[2-(ジメチルアミノ)フェニル]メチル}-2-(ピリジン-4-イル)-1,3-ジアジナン-1-イル)メチル]-N,N-ジメチルアニリン
- GANT-61
- 2-(4-ピリジニル)-1,3-ビス[2-(ジメチルアミノ)ベンジル]ヘキサヒドロピリミジン