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N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide

化学構造式
1048038-90-9
CAS番号.
1048038-90-9
化学名:
别名:
英語名:
N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide
英語别名:
COR167;N-(1-adamantyl)-6-isopropyl-4-oxo-1-pentyl-quinoline-3-carboxamide;N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide;N-((3s,5s,7s)-Adamantan-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinoline-3-carboxamide;3-Quinolinecarboxamide, 1,4-dihydro-6-(1-methylethyl)-4-oxo-1-pentyl-N-tricyclo[3.3.1.13,7]dec-1-yl-
CBNumber:
CB82554246
化学式:
C28H38N2O2
分子量:
434.61
MOL File:
1048038-90-9.mol

N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide 物理性質

比重(密度) :
1.15
溶解性:
DMF:5.0(Max Conc. mg/mL);11.5(Max Conc. mM)
Ethanol:3.0(Max Conc. mg/mL);6.9(Max Conc. mM)
外見 :
A crystalline solid

安全性情報

N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide 価格 もっと(2)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01TOC3556
SER 601 		1048038-90-9 10mg ￥50000 2020-09-21 購入
富士フイルム和光純薬株式会社(wako) W01TOC3556
SER 601 		1048038-90-9 50mg ￥241000 2020-09-21 購入

N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide 化学特性,用途語,生産方法

説明

SER-601 is a potent and selective peripheral cannabinoid (CB2) receptor agonist with 190-fold selectivity for CB2 over the central CB1 receptor (Kis = 6.3 and 1,220 nM, respectively). At 3 mg/kg, SER-601 has analgesic effects in a formalin-induced nocifensive study in mice without cannabis-like behavioral effects due to its low affinity for the CB1 receptor. SER-601 also has antidiabetic effects. Two to four week exposure to SER-601 ameliorates insulin resistance in vivo and increases insulin secretion and accumulation in pancreatic islets isolated from high-fat diet/streptozotocin (HFD/STZ)-induced diabetic mice.

使用

SER-601 is a 4-quinolone-3-carboxylic acid derivative and a selective cannabinoid CB2 receptor agonist (1,2,3). It exhibits analgesic and neuroprotective properties.

N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide 上流と下流の製品情報

原材料

準備製品

N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide 生産企業

Global( 12)Suppliers
名前 電話番号 電子メール 国籍 製品カタログ 優位度
CONIER CHEM AND PHARMA LIMITED 		+8618523575427
 sales@conier.com China 49391 58
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8449 60
Jinan ponder chemical co. LTD 0531-0000
thinklifescience@163.com China 19690 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
 sales@chemegen.com China 11289 58
Energy Chemical 021-58432009 400-005-6266
 marketing1@energy-chemical.com China 44843 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
 customer_service@efebio.com China 8739 58
TargetMol Chemicals Inc. 15002134094
 marketing@targetmol.cn China 28118 58
  • 1048038-90-9
  • N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide
  • N-((3s,5s,7s)-Adamantan-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinoline-3-carboxamide
  • N-(1-adamantyl)-6-isopropyl-4-oxo-1-pentyl-quinoline-3-carboxamide
  • 3-Quinolinecarboxamide, 1,4-dihydro-6-(1-methylethyl)-4-oxo-1-pentyl-N-tricyclo[3.3.1.13,7]dec-1-yl-
  • COR167
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