N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide

1048038-90-9

CAS-Nr.: 1048038-90-9

Englisch Name:: N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide

Synonyma:: COR167;N-(1-adamantyl)-6-isopropyl-4-oxo-1-pentyl-quinoline-3-carboxamide;N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide;N-((3s,5s,7s)-Adamantan-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinoline-3-carboxamide;3-Quinolinecarboxamide, 1,4-dihydro-6-(1-methylethyl)-4-oxo-1-pentyl-N-tricyclo[3.3.1.13,7]dec-1-yl-

CBNumber:: CB82554246

Summenformel:: C28H38N2O2

Molgewicht:: 434.61

MOL-Datei:: 1048038-90-9.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 12

N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide Eigenschaften

Dichte: 1.15

Löslichkeit: DMF:5.0(Max Conc. mg/mL);11.5(Max Conc. mM)
Ethanol:3.0(Max Conc. mg/mL);6.9(Max Conc. mM)

Aggregatzustand: A crystalline solid

Sicherheit

N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

SER-601 is a potent and selective peripheral cannabinoid (CB₂) receptor agonist with 190-fold selectivity for CB₂ over the central CB₁ receptor (K_is = 6.3 and 1,220 nM, respectively). At 3 mg/kg, SER-601 has analgesic effects in a formalin-induced nocifensive study in mice without cannabis-like behavioral effects due to its low affinity for the CB₁ receptor. SER-601 also has antidiabetic effects. Two to four week exposure to SER-601 ameliorates insulin resistance in vivo and increases insulin secretion and accumulation in pancreatic islets isolated from high-fat diet/streptozotocin (HFD/STZ)-induced diabetic mice.

Verwenden

SER-601 is a 4-quinolone-3-carboxylic acid derivative and a selective cannabinoid CB2 receptor agonist (1,2,3). It exhibits analgesic and neuroprotective properties.

N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 12)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49391	58
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Jinan ponder chemical co. LTD	0531-0000	thinklifescience@163.com	China	19690	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Energy Chemical	021-58432009 400-005-6266	marketing1@energy-chemical.com	China	44843	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	8739	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	28118	58

N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide
N-((3s,5s,7s)-Adamantan-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinoline-3-carboxamide
N-(1-adamantyl)-6-isopropyl-4-oxo-1-pentyl-quinoline-3-carboxamide
3-Quinolinecarboxamide, 1,4-dihydro-6-(1-methylethyl)-4-oxo-1-pentyl-N-tricyclo[3.3.1.13,7]dec-1-yl-
COR167
1048038-90-9