N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide
|
|
N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide 속성
- 밀도
- 1.15
- 용해도
- DMF:5.0(Max Conc. mg/mL);11.5(Max Conc. mM)
Ethanol:3.0(Max Conc. mg/mL);6.9(Max Conc. mM)
- 물리적 상태
- 결정성 고체
안전
N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide C화학적 특성, 용도, 생산
개요
SER-601 is a potent and selective peripheral cannabinoid (CB2) receptor agonist with 190-fold selectivity for CB2 over the central CB1 receptor (Kis = 6.3 and 1,220 nM, respectively). At 3 mg/kg, SER-601 has analgesic effects in a formalin-induced nocifensive study in mice without cannabis-like behavioral effects due to its low affinity for the CB1 receptor. SER-601 also has antidiabetic effects. Two to four week exposure to SER-601 ameliorates insulin resistance in vivo and increases insulin secretion and accumulation in pancreatic islets isolated from high-fat diet/streptozotocin (HFD/STZ)-induced diabetic mice.용도
SER-601 is a 4-quinolone-3-carboxylic acid derivative and a selective cannabinoid CB2 receptor agonist (1,2,3). It exhibits analgesic and neuroprotective properties.N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide 준비 용품 및 원자재
원자재
준비 용품
N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide 공급 업체
글로벌( 12)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49391 | 58 |
EMMX Biotechnology LLC | 888-539-0666 |
info@emmx.com | United States | 8449 | 60 |
Jinan ponder chemical co. LTD | 0531-0000 |
thinklifescience@163.com | China | 19690 | 58 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11289 | 58 |
Energy Chemical | 021-58432009 400-005-6266 |
marketing1@energy-chemical.com | China | 44843 | 58 |
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 |
customer_service@efebio.com | China | 8739 | 58 |
TargetMol Chemicals Inc. | 15002134094 |
marketing@targetmol.cn | China | 28118 | 58 |