Rho Kinase Inhibitor V

Rho Kinase Inhibitor V 価格

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Rho Kinase Inhibitor V 化学特性,用途語,生産方法

一般的な説明

A cell-permeable pyrazolyl carboxamide compound that acts as a potent, ATP-binding pocket-targeting inhibitor of ROCK-II (IC₅₀ = 1.5 nM) and effectively inhibits the myosin light chain 2 phosphorylation on Thr18/Ser19 in A7r5 cells (IC₅₀ = 72 nM). It afftects the activities of PKA, MRCK, Akt1 (IC₅₀ = 0.186, 1.19, and 1.41 μM, respectively) and CYP-450 enzymes (% inhibition of 2C9/2D6/3A4/1A2 at 10 μM = 87/40/1/20, respectively) only at much higher concentrations.

Rho Kinase Inhibitor V 上流と下流の製品情報

原材料

準備製品

Rho Kinase Inhibitor V 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
VDM Biochemicals	0330-2528181	sales@vdmbio.com	United States	510	64
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51456	80

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• 1072906-02-5
• Rho Kinase Inhibitor V
• Rho Kinase Inhibitor V - CAS 1072906-02-5 - Calbiochem
• 1,4-Benzodioxin-2-carboxamide, 2,3-dihydro-N-[4-(1H-pyrazol-4-yl)phenyl]-