プロピオン酸 ナトリウム 化学特性,用途語,生産方法
外観
白色, 結晶～粉末又は顆粒
定義
本品は、プロピオン酸(*)のナトリウム塩であり、次の化学式で表される。
参照表示名称：プロピオン酸
溶解性
水に易溶, エタノールに可溶。水に溶けやすく、エタノールにやや溶けやすい。
用途
防かび剤、保存料。
化粧品の成分用途
防腐剤
効能
抗真菌薬, 消毒薬
主な用途／役割
でんぷん系接着剤に使用される。
使用上の注意
大気中に放置すると、吸湿する。
説明
Sodium propanoate or sodium propionate is the sodium salt of propionic acid which has the chemical formula Na(C
2H
5COO).
化学的特性
Colourless crystals or, white or almost white powder, slightly hygroscopic.
使用
Sodium Propionate is an antimicrobial agent that is the sodium salt
of propionic acid. it occurs as colorless, transparent crystals or a gran-
ular crystalline powder. it is odorless or has a faint acetic–butyric acid
odor, and is deliquescent. it is prepared by neutralizing propionic acid
with sodium hydroxide. it is used in baked goods; nonalcoholic
beverages; cheeses; confections and frostings; gelatins, puddings, and
fillings; jams and jellies; meat products; and soft candy.
定義
ChEBI: An organic sodium salt comprising equal numbers of sodium and propionate ions.
反応性
It is produced by the reaction of propionic acid and sodium carbonate or sodium hydroxide.
生物活性
If sodium propionate is ingested or applied topically in an acid media, it becomes propionic acid. It oxidizes fatty acids, lowers pH values, and facilitates the citric acid cycle through interaction with coenzyme A. There has been evidence of heightened production of insulin in cows and sheep; the insulin later settles to an overall lower level.
Propionic acid inhibits 14CO2 production from palmitate in both control and methylmalonic fibroblasts; propionic acid also inhibited ureagenesis in rat liver slices. These findings may explain the fatty degeneration of the liver and hyperammonemia in propionic and methylmalonic acidemia. Propionic acidemia is an autosomal recessive disorder caused by a defect of propionyl–coenzyme A carboxylase. The main clinical findings are vomiting, lethargy, hypotonia, and metabolic ketoacidosis, and early clinical onset occurs during the neonatal period in ～80% of the patients.
安全性プロファイル
Moderately toxic by skin contact and subcutaneous routes. Mildly toxic by unspecified routes. An allergen. When heated to decomposition it emits toxic fumes of Na2O.
純化方法
Recrystallise it from H2O (solubility 10%) and dry by heating at 100o for 4hours. The solubility of the anhydrous salt in MeOH is 13% at 15o and 13.77% at 68o. It is insoluble in *C6H6 and Me2CO. [Henstock J Chem Soc 1341 1934, Beilstein 2 IV 701.]
プロピオン酸 ナトリウム 上流と下流の製品情報
原材料
準備製品