Boc-Glycine hydrazide
Boc-Glycine hydrazide 物理性質
- 融点 :
- 111-115
- 沸点 :
- 386.5±25.0 °C(Predicted)
- 比重(密度) :
- 1.139±0.06 g/cm3(Predicted)
- 貯蔵温度 :
- under inert gas (nitrogen or Argon) at 2–8 °C
- 外見 :
- solid
- 酸解離定数(Pka):
- 11.40±0.46(Predicted)
- 色:
- Beige
- InChI:
- InChI=1S/C7H15N3O3/c1-7(2,3)13-6(12)9-4-5(11)10-8/h4,8H2,1-3H3,(H,9,12)(H,10,11)
- InChIKey:
- MQBASTZLTYLEON-UHFFFAOYSA-N
- SMILES:
- C(NN)(=O)CNC(OC(C)(C)C)=O
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
| 主な危険性 |
Xi,Xn |
|
|
| Rフレーズ |
22 |
|
|
| 国連危険物分類 |
IRRITANT |
|
|
| HSコード |
2928009090 |
|
|
| 絵表示（GHS） |
|
| 注意喚起語 |
|
| 危険有害性情報 |
| コード |
危険有害性情報 |
危険有害性クラス |
区分 |
注意喚起語 |
シンボル |
P コード |
| H302 |
飲み込むと有害 |
急性毒性、経口 |
4 |
警告 |
|
P264, P270, P301+P312, P330, P501 |
| H315 |
皮膚刺激 |
皮膚腐食性/刺激性 |
2 |
警告 |
|
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
強い眼刺激 |
眼に対する重篤な損傷性/眼刺激 性 |
2A |
警告 |
|
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
呼吸器への刺激のおそれ |
特定標的臓器毒性、単回暴露； 気道刺激性 |
3 |
警告 |
|
|
|
| 注意書き |
| P260 |
粉じん/煙/ガス/ミスト/蒸気/スプレーを吸入しないこ と。 |
| P271 |
屋外または換気の良い場所でのみ使用すること。 |
| P280 |
保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。 |
|
Boc-Glycine hydrazide 価格
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
Boc-Glycine hydrazide 化学特性,用途語,生産方法
使用
Boc-Glycine hydrazide is used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
合成
N-Protected Hydrazides 2a-l; General Procedure The protected amino acid 1 (2 equiv) and EDAC (2 equiv) were dissolved in the minimum amount of CH2Cl2 at 0 C. The mixture was stirred at 0 C for 2 h. PhthNNH2 (1 equiv) was added and the mixture was stirred at 0 C for 1 h and then at r.t. overnight. Distillation of the solvent under reduced pressure gave a product which was dissolved in EtOAc and washed successively with 1 M KHSO4, sat. aq NaHCO3, and brine. The organic layer was then dried (Na2SO4), filtered, and concentrated in vacuo. The residue was precipitated with Et2O to yield compound 2. If necessary, the residue was purified by column chromatography (silica gel, hexane- EtOAc, 3:7 to 7:3). Compounds 4a-l; General Procedure Aminomethylated polystyrene resin (3 equiv; 1.1 mmol/g, 100-200 mesh) was conditioned for 10 min at r.t. in CH2Cl2. Then 2 (1 equiv) was added, and the mixture was slowly stirred for 24 h at r.t. The mixture was filtered and the solvent was evaporated in vacuo to give product 4. Compound 4h, yield 89%.
Boc-Glycine hydrazide 上流と下流の製品情報
原材料
準備製品
Boc-Glycine hydrazide 生産企業
Global( 117)Suppliers
6926-09-6()キーワード:
- 6926-09-6
- BOC-GLYCINE HYDRAZIDE
- BUTTPARK 77\04-08
- N-TERT-BUTOXYCARBONYLGLYCYLHYDRAZIDE
- Butoxycarbonylglycine hydrazide
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- tert-Butyl (2-hydrazino-2-oxoethyl)carbamate, 2-[(tert-Butoxycarbonyl)amino]acetohydrazide
- HydrazinocarbonylMethyl-carbaMic acid tert-butyl ester, 95%+
- tert-butyl (2-hydrazino-2-oxoethyl)carbamate
- tert-butyl N-(2-hydrazino-2-oxo-ethyl)carbamate
- tert-butyl N-(2-hydrazinyl-2-oxoethyl)carbamate
- tert-butyl N-(2-hydrazinyl-2-oxo-ethyl)carbamate
- tert-Butyl (2-hydrazinyl-2-oxoethyl)
- N-(2-hydrazino-2-keto-ethyl)carbamic acid tert-butyl ester
- N-(2-hydrazino-2-oxoethyl)carbamic acid tert-butyl ester
- Boc-Glycinehydrazide，98%
- Hydrazinocarbonylmethyl-carbamic acid tert-butyl ester
- tert-butyl N-[(hydrazinecarbonyl)methyl]carbamate
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- ert-butylN-(2-hydrazinyl-2-oxoethyl)carbamate
- Boc-Glycine hydrazide USP/EP/BP