3-メチルブタン酸3-[[3-(ホルミルアミノ)-2-ヒドロキシベンゾイル]アミノ]-8-ヘキシル-2,6-ジメチル-4,9-ジオキソ-1,5-ジオキソナン-7-イル 化学特性,用途語,生産方法
説明
Antimycin A
1 is an active component of the antimycin A antibiotic complex. It inhibits electron transport and is active against the plant pathogenic fungus
G. cingulate. Antimycin A
1 (3.3-160 μM) induces the synthesis of carotenoids in
M. marinum. It also inhibits ATP-citrate lyase (K
i = 29.5 μM).
化学的特性
Crystals. Soluble in alcohol, ether, acetone, and chloroform; slightly soluble in benzene, carbon tetrachloride, and petroleum ether; insoluble in water.
使用
Antimycin A1 is the most hydrophobic of the four analogues of the antimycin A complex. Like all antimycins, antimycin A1 exhibits potent antifungal, anthelmintic, insecticidal, antiviral and antitumor activity across a range of bioassays. Although broadly active as respiration inhibitors, more recent investigation has highlighted the importance of individual members of the complex as bioprobes. Antimycin A1 inhibits angiogenesis via a decrease in VEGF production caused by inhibition of HIF-1a activation.
定義
An antibiotic substance said to have strong fungicidal properties.
職業ばく露
Specific uses for antimycin A were
not found, however, antimycin A1, and antimycin A3 are
reported to be antibiotic substances produced by streptomyces
for use as a fungicide, possible insecticide and miticide.
Registered as a pesticide in the U.S.
輸送方法
UN2811 Toxic solids, organic, n.o.s., Hazard
Class: 6.1; Labels: 6.1-Poisonous materials, Technical
Name Required.
3-メチルブタン酸3-[[3-(ホルミルアミノ)-2-ヒドロキシベンゾイル]アミノ]-8-ヘキシル-2,6-ジメチル-4,9-ジオキソ-1,5-ジオキソナン-7-イル 上流と下流の製品情報
原材料
準備製品