인카드로닉
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인카드로닉 속성
- 녹는점
- 232-233°
- 끓는 점
- 564.2±60.0 °C(Predicted)
- 밀도
- 1.48±0.1 g/cm3(Predicted)
- 저장 조건
- 2-8°C
- 용해도
- 물(약간 용해됨), 메탄올(약간 용해됨)
- 산도 계수 (pKa)
- 0.61±0.10(Predicted)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 흰색에서 황백색까지
안전
인카드로닉 C화학적 특성, 용도, 생산
개요
Bisphonal, a new third generation drug, was launched in Japan for the treatment of osteoporosis. It can be prepared in two steps by heating cycloheptylamine, triethylorthoformate and diethyl phosphite followed by ester hydrolysis. The mechanism of action is not well understood. Bisphonal has no effect on bone mineralization but tightly binds to calcified bone matrix and inhibits bone resorption. It causes a decrease in the number and activity of osteoclasts (morphology and decrease in H+ secretion). They seem to undergo cell death with an impairment in the process of osteoclast formation. Bisphonal does not induce osteomalacia and its activity is partly mediated through osteoblasts (releases an inhibitor of osteoclast recruitment). It is a potent inhibitor of squalene synthase (50-fold) maybe by Mg2+ chelation or as a pyrophosphate mimic, undergoes practically no metabolism, and stimulates renal production of 1,25-dihydroxyvitamin D.용도
Incandronate is a bisphosphonate derivative. Bisphosphonates are most widely used as agents for treating osteoporosis and have also been used for other purposes such as herbicides, anticancer agents, and antiparasitics.인카드로닉 준비 용품 및 원자재
원자재
준비 용품
인카드로닉 공급 업체
글로벌( 11)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Beijing Comparison Pharmaceutical Technology Co., Ltd | 010-52878169 15701683040 |
sales@bjcomparison.com | China | 4739 | 58 |
| ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 |
sales@chem-strong.com | China | 18018 | 56 |
| Pharmasea Pharmaceutical Technology (Beijing) Co., Ltd | 010-57296878 15633144420 |
zhengzs2000@aliyun.com | China | 27 | 58 |
| Aikon International Limited | 025-58851090 13611564524 |
lwan@aikonchem.com | China | 15952 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 |
sales@rrkchem.com | China | 56057 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 |
marketing1@energy-chemical.com | China | 44843 | 58 |
| Wuhan Yingnuo Pharmaceutical Technology Co., Ltd. | +86-027-59232304 15387063101 |
2881924050@qq.com | China | 9904 | 58 |
| Nantong Hanfang Biotechnology Co. , Ltd. | 3674309880 |
hanfangpharma@126.com | China | 30968 | 58 |
| TargetMol Chemicals Inc. | 15002134094 |
marketing@targetmol.com | China | 24246 | 58 |