Adipotide

Adipotide 구조식 이미지
카스 번호:
상품명:
Adipotide
동의어(영문):
FTPP;Adipotide;FTPP peptide
CBNumber:
CB03128839
분자식:
포뮬러 무게:
0
MOL 파일:
Mol file

Adipotide 속성

안전

Adipotide C화학적 특성, 용도, 생산

Safety

A daily subcutaneous injection of Adipotide (0.43 mg/kg) is the optimal therapeutic dose for spontaneously obese macaques. It was demonstrated that the dosage of Adipotide is strongly correlated with body surface area and that its relative dose migrates from smaller to larger mammalian species (including humans). And animal studies show that Adipotide treatment is generally well tolerated. The major side effect is nephrotoxicity, which is generally mild and reversible. Decreases in serum phosphorus and potassium and urinary changes, including mild to marked glucosuria, mild to moderate proteinuria, and slight to mild increases in transitional/renal epithelial cells, have been noted throughout the dosing interval.

참고 문헌

[1] Kirstin F Barnhart. “A peptidomimetic targeting white fat causes weight loss and improved insulin resistance in obese monkeys.” Science Translational Medicine 3 108 (2011): 108ra112.

Adipotide 준비 용품 및 원자재

원자재

준비 용품


Adipotide 공급 업체

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