팔미틴산레티놀
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팔미틴산레티놀 속성
- 녹는점
- 28-29℃
- 끓는 점
- 546.51°C (rough estimate)
- 밀도
- 0.9668 (rough estimate)
- 굴절률
- 1.5250 (estimate)
- 인화점
- 194℃
- 저장 조건
- 2-8°C
- 용해도
- 클로로포름 (약간 용해됨), 에틸아세테이트 (약간 용해됨), 메탄올(살짝살짝용해됨)
- 물리적 상태
- 기름
- 색상
- 밝은 노란색에서 노란색까지
- Specific Gravity
- 0.90~0.93 (20℃)
- 수용성
- 에 용해됨클로로포름, 에테르 및 식물성 기름에 용해됩니다. 물에 불용성.
- Merck
- 13,10073
- BRN
- 1917366
- BCS Class
- 4
- 안정성
- 감광성
- InChIKey
- VYGQUTWHTHXGQB-YFAKFODJSA-N
- LogP
- 15.51 at 25℃
- CAS 데이터베이스
- 79-81-2(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | T,Xn,F | ||
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위험 카페고리 넘버 | 63-53-61-11 | ||
안전지침서 | 53-23-36/37/39-45-36/37-16-60 | ||
유엔번호(UN No.) | UN1170 - class 3 - PG 2 - Ethanol, solution | ||
WGK 독일 | 3 | ||
RTECS 번호 | VH6860000 | ||
F 고인화성물질 | 8-10-23 | ||
TSCA | Yes | ||
HS 번호 | 29362100 | ||
독성 | LD50 (10 day) in mice, rats (mg/kg): 6060, 7910 orally (Kamm) |
그림문자(GHS): | |||||||||||||||
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신호 어: | Danger | ||||||||||||||
유해·위험 문구: |
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예방조치문구: |
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팔미틴산레티놀 C화학적 특성, 용도, 생산
화학적 성질
95.0-100.5% Absorbance @325 nm ≥0.85%용도
vitamin A palmitate is known as a skin “normalizer.” It acts as an antikeratinizing agent, helping the skin stay soft and plump, and improving its water-barrier properties. Because of its impact on the skin’s water-barrier properties, it is useful against dryness, heat, and pollution. It is also an anti-oxidant and is suggested for use in sunscreens. Clinical studies with vitamin A palmitate indicate a significant change in skin composition, with increases in collagen, DnA, skin thickness, and elasticity. Vitamin A palmitate’s stability is superior to retinol.일반 설명
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards.Retinyl palmitate belongs to a category of compounds called retinoids, which are chemically similar to vitamin A. It exhibits a beneficial effect on vision, skin and immune function, inhibits cell proliferation and prevents cancer. It is an important dietary as well as a therapeutic compound.
Safety Profile
Mildly toxic by ingestion. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.Purification Methods
The palmitate is separated from retinol by column chromatography on water-deactivated alumina with hexane containing a very small percentage of acetone. It is also chromatographed on TLC silica gel G, using pet ether/isopropyl ether/acetic acid/water (180:20:2:5) or pet ether/acetonitrile/acetic acid/water (190:10:1:15) to develop the chromatogram. It is then recrystallised from propylene at low temperature (below -47o). [Beilstein 6 IV 4135.]팔미틴산레티놀 준비 용품 및 원자재
원자재
준비 용품
팔미틴산레티놀 공급 업체
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