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FMOC-4-[2-(BOC-아미노)에톡시]-L-페닐알라닌

FMOC-4-[2-(BOC-아미노)에톡시]-L-페닐알라닌 구조식 이미지

카스 번호:: 1013883-02-7

한글명:: FMOC-4-[2-(BOC-아미노)에톡시]-L-페닐알라닌

동의어(한글):: FMOC-4-[2-(BOC-아미노)에톡시]-L-페닐알라닌

상품명:: FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE

동의어(영문):: Fmoc-phe(2-Ae-Boc)-OH;Fmoc-4-[2-(Boc-amino)ethoxy]-Phe-OH;Fmoc-4-[2-(Boc-amino)ethoxy]-phenylalanine;FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE;N-Fmoc-4-[2-(Boc-amino)ethoxy]-L-phenylalanine;(9H-Fluoren-9-yl)MethOxy]Carbonyl 4-[2-((Tert-Butoxy)Carbonyl amino)ethoxy]-L-Phenylalanine;O-[2-[[(1,1-Dimethylethoxy)carbonyl]amino]ethyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-tyrosine;L-Tyrosine, O-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-;(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(2-((tert-butoxycarbonyl)amino)ethoxy)phenyl)propanoic acid;(2S)-3-[4-(2-{[(tert-butoxy)carbonyl]amino}ethoxy)phenyl]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid

CBNumber:: CB0432276

분자식:: C31H34N2O7

포뮬러 무게:: 546.61

MOL 파일:: Mol file

속성

안전

용도

공급 업체 71

FMOC-4-[2-(BOC-아미노)에톡시]-L-페닐알라닌 속성

끓는 점: 759.1±60.0 °C(Predicted)

밀도: 1.245±0.06 g/cm3(Predicted)

산도 계수 (pKa): 2.96±0.10(Predicted)

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

위험 등급	IRRITANT

그림문자(GHS):

신호 어:

Danger

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	P- 코드
H315	피부에 자극을 일으킴	피부부식성 또는 자극성물질	구분 2	경고	P264, P280, P302+P352, P321,P332+P313, P362
H318	눈에 심한 손상을 일으킴	심한 눈 손상 또는 자극성 물질	구분 1	위험	P280, P305+P351+P338, P310
H335	호흡 자극성을 일으킬 수 있음	특정 표적장기 독성 - 1회 노출;호흡기계 자극	구분 3	경고

예방조치문구:

P264	취급 후에는 손을 철저히 씻으시오.
P264	취급 후에는 손을 철저히 씻으시오.
P280	보호장갑/보호의/보안경/안면보호구를 착용하시오.
P302+P352	피부에 묻으면 다량의 물로 씻으시오.
P305+P351+P338	눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
P310	즉시 의료기관(의사)의 진찰을 받으시오. 삼켰다면 즉시 의료기관(의사)의 도움을 받으시오.
P321	(…) 처치를 하시오.
P332+P313	피부 자극이 생기면 의학적인 조치· 조언을 구하시오.
P362	오염된 의복을 벗고 세척 후에 재사용하기

FMOC-4-[2-(BOC-아미노)에톡시]-L-페닐알라닌 C화학적 특성, 용도, 생산

용도

FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.

Synthesis

Add O-[2-[[tert-butoxycarbonyl]amino]ethyl]-L-tyrosine (3.24g, 10mmol) in a 100mL three-necked flask equipped with magnetic stirring and a thermometer, with a mass concentration of 5 · 5% 21.2g of sodium carbonate aqueous solution, 20mL of 9-fluorenylmethyl-N-succinimidyl carbonate (3.37g, 10mmol) in tetrahydrofuran solution was added dropwise at room temperature, after the addition, the amidation reaction was carried out at room temperature, monitored by TLC To the end of the reaction. Concentrated to remove part of the solvent, acidified with 2N hydrochloric acid to pH 6~7, extracted with ethyl acetate, washed with saturated brine, concentrated, beaten with petroleum ether, filtered and dried to obtain a white solid O-alkyl-N-[ Fluorenylmethyloxycarbonyl]-L-tyrosine is 4.68g, the yield is 85.7%, the HPLC purity is 99.8%, and the ee value is 99.8%.

FMOC-4-[2-(BOC-아미노)에톡시]-L-페닐알라닌 준비 용품 및 원자재

원자재

준비 용품

FMOC-4-[2-(BOC-아미노)에톡시]-L-페닐알라닌 공급 업체

글로벌( 71)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19915	58
Alpha Biopharmaceuticals Co., Ltd	+86-15542445688	sales@alabiochem.com	China	888	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29798	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32760	60
Zhejiang ZETian Fine Chemicals Co. LTD	+8618957127338	stella@zetchem.com	China	2141	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10297	58
Chengdu Aslee Biopharmaceuticals, Inc.	28-85305008		CHINA	964	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30253	58
GL Biochem (Shanghai) Ltd.	+86-021-61263370 +86-18901917034		CHINA	3904	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19743	58

FMOC-4-[2-(BOC-아미노)에톡시]-L-페닐알라닌 관련 검색:

Fmoc-D-Arg(Pbf)-OH Fmoc-Asn(Trt)-OH Fmoc-L-HoSer(OTBMS)-OH FMOC-LYS(BOC)(ME)-OH FMOC-S-trityl-L-cysteine 4-(FMOC-AMINO)-TETRAHYDROPYRAN-4-CARBOXYLIC ACID D-2-TRIFLUOROMETHYLPHENYLALANINE FMOC-D-2-TRIFLUOROMETHYLPHENYLALANINE FMOC-L-2-TRIFLUOROMETHYLPHENYLALANINE BOC-D-2-TRIFLUOROMETHYLPHENYLALANINE FMOC-L-4-TERT-BUTYL-PHE L-Phenylalanine, 3-[(1,1-dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]- Fmoc-phe(2-Ae-Z)-OH Fmoc-S-Trityl-L-penicillamine Fmoc-Phe(4-CF2H)-OH FMOC-D-4-CARBAMOYLPHE Fmoc-Pen(2-BA-OAll)OH