N-tert-부톡시카르보닐-1,6-헥산디아민
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N-tert-부톡시카르보닐-1,6-헥산디아민 속성
- 끓는 점
- 106-110 °C (0.3 mmHg)
- 밀도
- 0.965 g/mL at 20 °C(lit.)
- 굴절률
- n
20/D 1.462
- 인화점
- 125 °C
- 저장 조건
- Keep in dark place,Inert atmosphere,2-8°C
- 용해도
- 디클로로메탄과 에틸 아세테이트에 용해됩니다.
- 산도 계수 (pKa)
- 12.93±0.46(Predicted)
- 물리적 상태
- 점성 액체
- 색상
- 맑은 연한 노란색
- 감도
- Air Sensitive
- BRN
- 2089264
- InChIKey
- RVZPDKXEHIRFPM-UHFFFAOYSA-N
- CAS 데이터베이스
- 51857-17-1(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | C | ||
---|---|---|---|
위험 카페고리 넘버 | 34 | ||
안전지침서 | 26-36/37/39-45 | ||
유엔번호(UN No.) | UN 2735 8/PG 2 | ||
WGK 독일 | 3 | ||
F 고인화성물질 | 10-34 | ||
위험 등급 | 8 | ||
포장분류 | III | ||
HS 번호 | 29241900 |
N-tert-부톡시카르보닐-1,6-헥산디아민 C화학적 특성, 용도, 생산
화학적 성질
Off-White Solid용도
N-Boc-1,6-diaminohexane is used to prepare 1,3-Bis[6-(Boc-amino)hexyl]urea by reacting with carbonyl dichloride in the presence of triethylamine. Further, it is used as a reagent for the introduction of a C6-spacer.주요 응용
N-Boc-1,6-hexanediamine can be used as a linear hexyl spacer (C6-spacer) to synthesize:Biodegradable poly(disulfide amine)s for gene delivery.
A multifunctional dendrimer for theranostics.
Polyamide platinum anti-cancer complexes designed to target cancer specific DNA sequences.
Self-assembled monolayers (SAMs) that resist adsorption of proteins.
[N-(6-(4-Hydroxy-6-isopropylamino-1,3,5-triazin-2-ylamino)hexyl)-5-hydroxy-1,4-naphthoquinone-3-propionamide] (JUG-HATZ), which can be used in designing electrochemical immunosensors.
제조 방법
synthesis of N-BOC-1,6-diaminohexane: 1,6-Diaminohexane 3 (Fig. 1) (100 g, 0.86 mol) was dissolved in CH2Cl2 (300 ml) and cooled in an ice bath to 0–3°C. To the stirred solution 0.3 eq. di-tert-butyl bicarbonate (62.6 g, 0.29 mol) was added slowly over a period of 1 h. The reaction was allowed to warm up to r.t., and proceeded overnight. The reaction mixture was extracted with saturated aqueous NaHCO3 (50 ml, three times). The organic phases were pooled, dried, and evaporated under reduced pressure. The resulting oil was dissolved in 200 ml, 1 N HCl and extracted with ether. The aqueous phase was washed with ether, made basic to a pH of 10 with aqueous 2 N NaO3, and extracted with ethyl acetate. The organic phases were pooled, dried, and evaporated under reduced pressure. The resulting oil was dissolved in 200 ml, 1 N HCL and extracted with ether. The aqueous phase was washed with ether, made basic to a pH of 10 with aqueous 2 N NaOH, and extracted with ethyl acetate. The organic extracts were pooled, dried over Na2SO4 and evaporated to give 10.5 g of homogeneous N-BOC-1, 6- diaminohexane 2c (Fig. 1) as a yellow oil which was used without further purification.TLC Rf 0.51; 1H NMR (CDCL3) d 4.54 (bs, 1H; NH), 3.05 1 2.62 (m, 4H; NCH2), 1.41 (m, 9H; CH3), 1.29 (m, 8H; CH2).
Evaluation of aminoalkylmethacrylate nanoparticles as colloidal drug carrier systems. Part I: synthesis of monomers, dependence of the physical properties on the polymerization methods
N-tert-부톡시카르보닐-1,6-헥산디아민 준비 용품 및 원자재
원자재
Boc-6-AMinocaproic acid
tert-부틸아지도포르메이트
카르밤산,(5-시아노펜틸)-,1,1-디메틸에틸에스테르(9CI)
Carbonic acid, bis(1,1-dimethylethyl) ester
tert-부틸(6-aMino-6-oxohexyl)carbaMate
6-AZIDO-N-BOC-헥실아민
헥사메틸렌디아민
디 -Tert- 부틸 디 카보네이트
1,6-비스(tert-부톡시카르보닐아미노)헥산
tert-Butyl phenyl carbonate
준비 용품
N-tert-부톡시카르보닐-1,6-헥산디아민 공급 업체
글로벌( 202)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21667 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32836 | 60 |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 |
figo.gao@foxmail.com | China | 7621 | 58 |
Accela ChemBio Inc. | +1-858-6993322 |
info@accelachem.com | United States | 19447 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49392 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
factory@coreychem.com | China | 29825 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 |
sales@tnjchem.com | China | 34571 | 58 |