NSC632839염산염
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NSC632839염산염 속성
- 저장 조건
- Store at +4°C
- 용해도
- DMSO: ≥2mg/mL(가온)
- 물리적 상태
- 가루
- 색상
- 희미한 노란색에서 어두운 노란색까지
- 안정성
- 제공된 대로 구매일로부터 2년 동안 안정적입니다. DMSO의 솔루션은 최대 1개월 동안 -20°에서 보관할 수 있습니다.
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
NSC632839염산염 C화학적 특성, 용도, 생산
용도
Protein ubiquitination is a dynamic process that can be reversed by deubiquitinating enzymes (DUBs) that remove ubiquitin from proteins, sparing them from degradation by the proteasome. The DUBs have been divided into various groups, the largest being the ubiquitin-specific proteases (USPs). NSC 632839 inhibits USP2 and USP7 as well as the ubiquitin-like SUMO peptidase SENP2 with EC50 values of 45, 37, and 9.8 μM, respectively. It is reported to inhibit apoptosis through a Bcl-2-dependent and apoptosome-independent pathway of caspase activation (IC50 = 15.7 μM in cells sensitized by E1A, an adenoviral oncogene).생물학적 활성
Inhibitor of ubiquitin isopeptidase activity that displays no effect on the proteolytic activity of the proteasome. Induces apoptosis via a Bcl-2-dependent and apoptosome-independent pathway of caspase activation (IC 50 values are 15.65 and 16.23 μ M in E1A and E1A/C9CN cells respectively).NSC632839염산염 준비 용품 및 원자재
원자재
준비 용품
NSC632839염산염 공급 업체
글로벌( 98)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32760 | 60 |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 |
laboratory@coreychem.com | China | 30253 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 |
sales@hzclap.com | CHINA | 6313 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 |
sales@invivochem.cn | United States | 6393 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 |
sales@molcore.com | China | 49739 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 |
support@targetmol.com | United States | 19973 | 58 |
ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 |
trendseenbio@gmail.com | China | 11681 | 58 |
Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 |
product@acmec-e.com | China | 33350 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
Amadis Chemical Company Limited | 571-89925085 |
sales@amadischem.com | China | 131980 | 58 |
NSC632839염산염 관련 검색:
5-(2-HYDROXY-BENZYLIDENE)-THIAZOLIDINE-2,4-DIONE
4-Chloro-N,N-diethylbenzaMide, 97%
4-Chloro-N,N-di-n-propylbenzaMide, 97%
TIMTEC-BB SBB006342
NSC781406
2,4-Thiazolidinedione,5-[(4-hydroxy-3-methoxyphenyl)methylene]-
4-Chloro-N,N-diisopropylbenzamide
Pifithrin-μ
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1,3-Bis(4-aminophenyl)urea
5-(4-iodobenzylidene)rhodanine
S3I-201
NSC228155
NSC23005 Sodium
HAMNO
NSC 247030
CP671305
NSC 42834