ChemicalBook >제품 카탈로그 >NSC781406

NSC781406

NSC781406 구조식 이미지

카스 번호:: 1676893-24-5

상품명:: NSC781406

동의어(영문):: NSC781406;NSC-781406;NSC 781406;NSC781406, 10 mM in DMSO;NSC781406;NSC-781406;NSC 781406;NSC781406,Phosphoinositide 3-kinase,NSC 781406,NSC-781406,PI3K,Mammalian target of Rapamycin,Inhibitor,inhibit,mTOR;2,4-difluoro-N-[2-methoxy-5-[4-[3-[4-(methylsulfonyl)-1-piperazinyl]-1-propyn-1-yl]-6-quinolinyl]-3-pyridinyl]-benzenesulfonamide;Benzenesulfonamide, 2,4-difluoro-N-[2-methoxy-5-[4-[3-[4-(methylsulfonyl)-1-piperazinyl]-1-propyn-1-yl]-6-quinolinyl]-3-pyridinyl]-

CBNumber:: CB43334188

분자식:: C29H27F2N5O5S2

포뮬러 무게:: 627.68

MOL 파일:: 1676893-24-5.mol

속성

안전

용도

공급 업체 39

NSC781406 속성

끓는 점: 775.1±70.0 °C(Predicted)

밀도: 1.52±0.1 g/cm3(Predicted)

저장 조건: Store at -20°C

용해도: DMF: 10mg/mL; DMSO: 20mg/mL; DMSO:PBS (pH 7.2) (1:4): 0.2mg/mL

물리적 상태: 고체

산도 계수 (pKa): 6.23±0.40(Predicted)

색상: White to off-white

안전

NSC781406 C화학적 특성, 용도, 생산

개요

NSC 781406 is a dual inhibitor of PI3K and mammalian target of rapamycin (mTOR; IC₅₀s = 2.0, 9.4, 2.7, 14, and 5.4 nM for PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ, and mTOR, respectively). It inhibits cell growth in the NCI-60 panel of cancer cell lines (mean GI₅₀ = 65 nM). NSC 781406 (30 mg/kg) reduces tumor volume in a BEL-7404 hepatic cancer mouse xenograft model.

NSC781406 준비 용품 및 원자재

원자재

준비 용품

NSC781406 공급 업체

글로벌( 39)공급 업체

공급자	전화	이메일	국가	제품 수	이점
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32965	60
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52924	58
Shanghai Boyle Chemical Co., Ltd.		sales@boylechem.com	China	2922	55
MedChemexpress LLC	021-58955995	sales@medchemexpress.cn	United States	4861	58
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266		China	4573	55
YouCoChem (Beijing) Chemical Technology Co., Ltd.	18800159827	youcochem@163.com	China	161	50
ShangHai Biochempartner Co.,Ltd	17754423994 17754423994	2853530910@QQ.com	China	8011	62
Shanghai Chaolan Chemical Technology Center	021-QQ：65489617 15618227136	Sales@ATKchemical.com	China	7312	58

NSC781406 관련 검색:

CP671305 5-(2-HYDROXY-BENZYLIDENE)-THIAZOLIDINE-2,4-DIONE 4-Chloro-N,N-diethylbenzaMide, 97% 4-Chloro-N,N-di-n-propylbenzaMide, 97% TIMTEC-BB SBB006342 2,4-Thiazolidinedione,5-[(4-hydroxy-3-methoxyphenyl)methylene]- 4-Chloro-N,N-diisopropylbenzamide Pifithrin-μ 2-Pyridinecarbothioamide, N-2-pyridinyl- 1,3-Bis(4-aminophenyl)urea 5-(4-iodobenzylidene)rhodanine S3I-201 NSC228155 NSC632839hydrochloride NSC23005 Sodium HAMNO NSC 247030 NSC 42834