11-[[2-[(DIETHYLAMINO)METHYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE
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11-[[2-[(DIETHYLAMINO)METHYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE 속성
- 끓는 점
- 573.2±45.0 °C(Predicted)
- 밀도
- 1.171
- 저장 조건
- room temp
- 용해도
- DMSO: 가용성 5mg/mL(투명 용액, 가열)
- 산도 계수 (pKa)
- 11.29±0.20(Predicted)
- 물리적 상태
- 가루
- 색상
- 흰색에서 베이지색
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
11-[[2-[(DIETHYLAMINO)METHYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE C화학적 특성, 용도, 생산
용도
AF-DX 116 has been used as an M2 muscarinic acetylcholine receptor (M2AChR) selective antagonist to study the influence of M2AChR in the regulation of both basal and carbachol-stimulated long-term potentiation at the dentate gyrus (DG-LTP) and pro-nerve growth factor (proNGF) secretion in hippocampal cells of young diabetic rats.생물학적 활성
Selective M 2 muscarinic receptor antagonist. K i values are 64, 417, 786, 211 and 5130 nM for human recombinant M 2 , M 1 , M 3 , M 4 and M 5 muscarinic receptors, respectively.Biochem/physiol Actions
AF-DX 116 raises blood pressure and heart rate in a rat model of hypotension induced by repeated cold stress. Thus, it may be used as a therapeutic for hypotension related to vagotonia type autonomic dysfunction.11-[[2-[(DIETHYLAMINO)METHYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE 준비 용품 및 원자재
원자재
준비 용품
11-[[2-[(DIETHYLAMINO)METHYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE 공급 업체
글로벌( 55)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32760 | 60 |
Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49391 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
Alfa Chemistry | |
Info@alfa-chemistry.com | United States | 24072 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 |
jkinfo@jkchemical.com | China | 96815 | 76 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 |
3bsc@sina.com | China | 15848 | 69 |
Ascent Scientific | 4401179829988 |
customerservice@ascentscientific.co.uk | United Kingdom | 279 | 60 |
HangZhou YuHao Chemical Technology Co., Ltd. | 0571-82693216 |
info@yuhaochemical.com | China | 2031 | 58 |
Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51471 | 80 |
11-[[2-[(DIETHYLAMINO)METHYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE 관련 검색:
Hexamethyldisilazane
CHEMBRDG-BB 4015189
DIMETHYL-PIPERIDIN-2-YLMETHYL-AMINE
1-ethylpiperidine-2-methylamine
C-(1-METHYL-PIPERIDIN-2-YL)-METHYLAMINE
Methyl[(1-methylpiperidin-2-yl)methyl]amine
3-Amino-2-phenylamino-pyridine
ETHYL[(1-METHYLPIPERIDIN-2-YL)METHYL]AMINE
5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one
ETHYL[(1-ETHYLPIPERIDIN-2-YL)METHYL]AMINE
2-(2-methylpiperidin-1-yl)ethanamine
2-amino-N-(3-pyridinyl)benzamide
(1-ETHYL-2-PIPERIDINYL)-N-METHYLMETHANAMINE
2-(2-DIETHYLAMINOETHYL)PIPERIDINE
11-[[2-[(DIETHYLAMINO)METHYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE