헥사메틸다이실라잔

헥사메틸다이실라잔 속성

헥사메틸다이실라잔 C화학적 특성, 용도, 생산

화학 반응

헥사 메틸 디 실라 잔 액체. 헥사 메틸 디 실록산을 생성 쉽게 가수 분해와 NH3를 방출. 알코올이나 실란 또는 알콕시 실란 메틸 아릴 옥시기 메틸 페놀 반응에 촉매의 존재. 무수 염화수소 반응 및 방출과 NH3 또는 NH4Cl, trimethylchlorosilane가 생성됩니다. 시스템에서 NH3와 반응 trimethylchlorosilane 있습니다. N 원자에 제공되는 유기 합성 반응 시약의 소수​​성 연기가 난 실리카 표면 처리 에이전트로, 첨가제 탄화 규소 섬유, 내열성 및 강도를 향상시키기 위해 탄화 규소 섬유, 또한 코팅으로 사용될 수로 사용할 수 있습니다 반대로 침전 대리인. 및 유기 규소 화합물의 제조.

용도

HMDS 헥사 메틸 디 실라 잔 은 약제 생합성 (예 : amikacin, penicillin, cephalosporins, fluorouracil 및 페니실린 유도체의 종류), 항생제의 히드 록실 보호제에서 메틸 실란 알킬화로 주로 사용됩니다. 규조토의 표면 처리제, 백색 카본 블랙, 티타늄 및 반도체 산업의 포토 레지스트의 블론드 첨가제로서 인열 저항성 및 발수성 처리제로 사용될 수 있습니다.

포장, 보관 및 운송

Hexamethydisilazane 보관과 관련하여 시원하고 건조한 장소에 밀폐 된 용기에 보관해야합니다.

개요

Hexamethyldisilazane is a bulk organo silicon compound, being a quite useful silanizing agent. It is a reagent for the preparation of trimethylsilyl derivatives. It can also be used to dehydrate cells of biomaterials for scanning electron microscopy (SEM). Moreover, it is an adhesion promoter for photoresist in photolithography, and is also useful in the pyrolysis-gas chromatography-mass spectrometry to enhance the detectability of compounds with polar functional groups.

화학적 성질

Hexamethyldisilazane, also known as HMDS, is an important organosilicon compound, a colorless and transparent liquid. It is readily hydrolyzed and gives off NH3 to produce hexamethyldisilyl ether. In the presence of a catalyst, it reacts with alcohols or phenols to produce trimethylalkoxysilane or trimethylaroxysilane. Reacts with anhydrous hydrogen chloride, releasing NH3 or NH4Cl, to produce trimethylchlorosilane.

물리적 성질

Colorless transparent and easy flowing liquid. Boiling point 125℃, relative density 0.76 (20/4℃). Soluble in organic solvents, it will be rapidly hydrolyzed in contact with air to form trimethylsilanol and hexamethyldisilyl ether.

용도

Hexamethyldisilazane mainly used as methyl silane alkylation (such as amikacin, penicillin, cephalosporins and kinds of penicillin derivatives), hydroxyl protectants of antibiotics. It is used as surface treatment agent of diatomite, white carbon black, titanium and blond additives of photoresist in the semiconductor industry. It is used as treatment agent of tearing strength resistance. It is used as a solvent in organic synthesis and organometallic chemistry. It is used as an adhesion promoter for photoresist in photolithography. it is used for the preparation of trimethylsilyl ethers from hydroxy compounds. It is used as an alternative to critical point drying during sample preparation in electron microscopy. It is added to analyte to get silylated diagnostic products during pyrolysis in gas chromatography- mass spectrometry.

정의

ChEBI: Hexamethyldisilazane is an N-silyl compound obtained from ammonia by replacement of two of the hydrogens with trimethylsilyl groups. Hexamethyldisilazane is a derivatisation agent used in gas chromatography mass spectrometry applications. It has a role as a chromatographic reagent. It derives from a hydride of an ammonia.

일반 설명

Hexamethyldisilazane appears as a liquid. May be toxic by ingestion. Irritates skin and eyes. Vapors are heavier than air. May emit highly toxic nitrogen oxide fumes when heated to decomposition. Used to deactivate chromatography support materials and to promote adhesion of photoresists in the electronics industry.

공기와 물의 반응

Highly flammable. Moisture sensitive.

반응 프로필

Hexamethyldisilazane reacts with many carbonyl containing organic compounds to generate gaseous ammonia. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

위험도

Flammable, moderate fire risk.

건강위험

Inhalation or contact with material may irritate or burn skin and eyes. Fire may produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.

Purification Methods

A possible impurity is Me3SiCl. Wash it well with pet ether and fractionate it through a vacuum jacketed column packed with Helipac using a reflux ratio of 10:1. [Langer et al. J Org Chem 23 50 1958, Beilstein 4 IV 4014.]

참고 문헌

Deng, Xiang. "Hexamethyldisilazane." Synlett 2011.06(2011):881-882. Chiavari, G, D. Fabbri, and S. Prati. "Gas chromatographic-mass spectrometric analysis of products arising from pyrolysis of amino acids in the presence of hexamethyldisilazane." Journal of Chromatography A922.1–2(2001):235-241.
Nation, J. L. "A new method using hexamethyldisilazane for preparation of soft insect tissues for scanning electron microscopy." Stain Technology 58.6(1983):347-51.
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헥사메틸다이실라잔 준비 용품 및 원자재

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헥사메틸다이실라잔 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Ningxia Jinhua Chemical Co.,Ltd	025-52279164	info@nxjhchem.com	China	79	58
Wuhan Kemi-Works Chemical Co., Ltd.	+86-2785736489 +8618171418573	sales@kemiworks.com	China	728	58
Zouping mingyuan import & export trading co., ltd	+86-0543-2240078 +8618364991597	myzhao793@163.com	China	994	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5893	58
Iota silicone oil (Anhui) Co.,ltd.	+86-15255260163	sales05@siliconeoil.net	China	311	58
Hebei Mojin Biotechnology Co., Ltd	+86 13288715578 +8613288715578	sales@hbmojin.com	China	12837	58
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	5858	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971 +86-17331933971	deasea125996@gmail.com	China	2472	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29791	60
Jiangxi New jiayi New Materials Co., Ltd.	15988280056	mina@xjysi.com	CHINA	27	55

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