GABEXATE

GABEXATE 구조식 이미지
카스 번호:
39492-01-8
상품명:
GABEXATE
동의어(영문):
GABEXATE;Gabexate USP/EP/BP;GabexateMesylateBase;4-[(6-Guanidinohexanoyl)oxy]benzoic acid ethyl ester;ethyl 4-[6-(diaminomethylideneamino)hexanoyloxy]benzoate;diaminomethylidene-[6-(4-ethoxycarbonylphenoxy)-6-oxohexyl]ammonium;4-[[6-[[Amino(imino)methyl]amino]-1-oxohexyl]oxy]benzoic acid ethyl ester;Benzoic acid, 4-[[6-[(aminoiminomethyl)amino]-1-oxohexyl]oxy]-, ethylester;[N'-[5-(4-ethoxycarbonylphenoxy)carbonylpentyl]carbamimidoyl]azanium methanesulfonate
CBNumber:
CB1258637
분자식:
C16H23N3O4
포뮬러 무게:
321.37
MOL 파일:
39492-01-8.mol

GABEXATE 속성

끓는 점
472.2±55.0 °C(Predicted)
밀도
1.20±0.1 g/cm3(Predicted)
저장 조건
Desiccate at RT
용해도
DMSO(약간 용해됨), 메탄올(약간 용해됨)
물리적 상태
고체
물리적 상태
단단한 모양
산도 계수 (pKa)
13.83±0.70(Predicted)
색상
하얀색

안전

GABEXATE C화학적 특성, 용도, 생산

용도

Gabexate mesylate is used in combination with somatostatin and octreotide in the treatment of severe acute pancreatitis in elderly patients.

생물학적 활성

Serine protease inhibitor; inhibits trypsin, plasmin, plasma kallikrein and thrombin (IC 50 values are 9.4, 30, 41 and 110 mM respectively). Antithrombotic in vitro and in vivo . Also inhibits LPS-induced TNF- α production, probably by inhibiting NF- κ B and AP-1 activation.

GABEXATE 준비 용품 및 원자재

원자재

준비 용품


GABEXATE 공급 업체

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