[S-(R*,R*)]-2-아미노-3-메틸-N-[2-(4-모르폴리닐)에틸]펜탄아미드이염산염

[S-(R*,R*)]-2-아미노-3-메틸-N-[2-(4-모르폴리닐)에틸]펜탄아미드이염산염
[S-(R*,R*)]-2-아미노-3-메틸-N-[2-(4-모르폴리닐)에틸]펜탄아미드이염산염 구조식 이미지
카스 번호:
1243259-19-9
한글명:
[S-(R*,R*)]-2-아미노-3-메틸-N-[2-(4-모르폴리닐)에틸]펜탄아미드이염산염
동의어(한글):
[S-(R*,R*)]-2-아미노-3-메틸-N-[2-(4-모르폴리닐)에틸]펜탄아미드이염산염
상품명:
[S-(R*,R*)]-2-AMino-3-Methyl-N-[2-(4-Morpholinyl)ethyl]pentanaMide Dihydrochloride
동의어(영문):
LM11A-31;LM11A-31 BHS;LM11A-31 HCl;LM11A 31 2HCl;(2S,3S)-2-AMINO-3-;LM11A-31 (hydrochloride);LM11A-31 D8 dihydrochloride;LM11A-31 dihydrochloride salt;LM11A-31 dihydrochloride (LM11A-31 BHS);(2S,3S)-2-AMINO-3-METHYL-N-(2-MORPHOLIN-4-YLETHYL)PENTANAMIDE
CBNumber:
CB12621190
분자식:
C12H26ClN3O2
포뮬러 무게:
279.81
MOL 파일:
1243259-19-9.mol

[S-(R*,R*)]-2-아미노-3-메틸-N-[2-(4-모르폴리닐)에틸]펜탄아미드이염산염 속성

녹는점
>68°C (dec.)
저장 조건
-20°C
용해도
DMSO(최대 20mg/ml) 또는 에탄올(최대 30mg/ml)에 용해됩니다.
물리적 상태
고체
물리적 상태
단단한 모양
색상
옅은 노랑
안정성
제공된 대로 구매일로부터 1년 동안 안정적입니다. DMSO 또는 에탄올 용액은 -20°C에서 최대 1개월 동안 보관할 수 있습니다.

안전

HS 번호 9999999999

[S-(R*,R*)]-2-아미노-3-메틸-N-[2-(4-모르폴리닐)에틸]펜탄아미드이염산염 C화학적 특성, 용도, 생산

개요

LM11A-31 is a p75 neurotrophin receptor (p75NTR) ligand that inhibits nerve growth factor (NGF) binding to p75NTR-Fc (A2 = 1,192 nM). It inhibits DNA damage in and promotes survival of hippocampal neuronal cultures in a p75NTR- and concentration-dependent manner. LMA11A-31 also inhibits proNGF-induced cell death of mature oligodendrocytes. In vivo, LMA11A-31 (10-100 mg/kg) improves motor function and coordination in the weight-bearing open-field test and nonweight-bearing swim test and increases survival of oligodendrocytes in a mouse model of spinal contusion injury. It prevents and/or reverses atrophy of forebrain cholinergic neurites and cortical dystrophic neurites in Thy-1 hAPPLond/Swe and Tg2576 mice with mid- to late stage Alzheimer''s disease. It also reduces excessive alcohol self-administration in rats and decreases huntingtin (Htt) aggregate formation and striatal cholinergic degeneration in the R6/2 mouse model of Huntington''s disease.

용도

(2S,3S)-2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]pentanamide is used for the preparation of peptideamides for treatment of retroviral infection.

[S-(R*,R*)]-2-아미노-3-메틸-N-[2-(4-모르폴리닐)에틸]펜탄아미드이염산염 준비 용품 및 원자재

원자재

준비 용품


[S-(R*,R*)]-2-아미노-3-메틸-N-[2-(4-모르폴리닐)에틸]펜탄아미드이염산염 공급 업체

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[S-(R*,R*)]-2-아미노-3-메틸-N-[2-(4-모르폴리닐)에틸]펜탄아미드이염산염 관련 검색:

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